An Insoluble Problem? Overcoming Oral Drug Solubility Challenges With Functional Polymers

By Dr Thomas Endres, Head of New Products & Materials, Evonik Corporation

Almost half of currently marketed drug products, and around 90 percent of those in clinical development are associated with poor drug solubility or permeability. This article is part one of a two-part series on solubility enhancement. Here we will discuss the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility. We will also address common questions on the topic.