ORAL DRUG DELIVERY ARTICLES
The Resurgence Of Fervor For Oral Delivery
In this article, Chief Editor Tom von Gunden reports on the science and technology boosting the rise in attention to oral methods for advanced drug and biologics delivery. The insights he illuminates include innovative approaches to increasing permeability, solubility, and bioavailability, as well as expanding the types and sizes of therapeutic payloads formulated for oral administration.
ORAL DRUG DELIVERY VIDEOS
In this episode of Supplier Horizons, host Tom von Gunden talks with Chief Commercial Officer Christian Jones of nanoparticle technology developer Nanoform about innovation in drug and biologics delivery. The discussion covers aspects of patient centricity such as aging populations, in-home self-administration, and personalized medicine. It also focuses on the use of nanotechnology in the delivery of high concentration formulations via oral and subcutaneous routes of administration.
In this segment of the Drug Delivery Leader Live online event, Next-Gen Drug Delivery: Rethinking Routes For New Therapies, James Wabby, head of global regulatory affairs for emerging device technologies and combination products at AbbVie, discuses critical components of an integrated regulatory strategy for advanced therapy product development.
Principal Scientist George Mihov and Global Biomaterials Director Lukasz Koroniak from DSM-Firmenich join Supplier Horizons host Tom von Gunden to discuss partnering with pharma on formulation development. Among the topics covered are translational research, materials development, and complex molecules required for biologic-based therapies.
In this segment of the Drug Delivery Leader Live event New FDA QMSR: Its Role in Part 4 Compliance for Combination Products, DDL Executive Editor Fran DeGrazio enlists consultants Laurie Auerbach of Compliance Prodigies and Ed Bills of Edwin Bills Consultant to summarize where Part 4 is documented in the new guidance.
ORAL DRUG DELIVERY RESOURCES
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![GettyImages-950086574-oral-solid-OSD-pill-tablet-capsule-development]( "Platform Reduces Product Development Time And Cost By 30%")
Using innovative capsule-filling equipment and processing technology, and mini-tablet and drug-layered beadlet manufacturing, you can have an adaptable, easily modified formulation.
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![Clean room industrial laboratory manufacturing GettyImages-1344379591]( "Achieving New Heights By Expanding Services, Talent, And Facilities")
As you aim to reduce costs and ensure on-time delivery, discover the opportunities for drug formulation and commercial supply that can advance your therapy to the clinic and beyond.
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![iStock-1227501239-medicine-tablet-capsule]( "Rational Design & Development Of Lipid- Filled Hard Capsules")
With the increasing percentage of water-insoluble or low permeable new therapeutic entities among drug pipelines, lipid-based drug delivery systems have become an important tool for formulation development.
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![GettyImages-1287846309-research-lab-computer-graph-data]( "An Integrated Radiolabelled Study: Determine Mass Balance Metabolite Profile & Absolute Bioavailability")
The study assessed the absorption and disposition of nolasiban after oral and IV administrations and enabled determination of mass balance, routes and rates of excretion and metabolism and absolute bioavailability.
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![GettyImages-1287840962-modeling-simulation]( "How To Leverage Modeling And Simulation In The Candidate Development Stage")
Modeling and simulation provides another way to predict the clinical performance of a molecule, based on a robust and holistic approach, before investing the required time and money.
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![GettyImages-1327624070-lab-research-development]( "Streamlining The Path To Phase 1 For Challenging APIs")
A comprehensive approach to evaluating drug molecules for the selection of a lead solid form and formulation can significantly accelerate development timelines and limit risks in later development.
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![GettyImages-1087219142 Scientist Using Digital Tablet Computer In Manufacturing Laboratory]( "Leveraging Tools To Create Optimized Solutions")
Review the key trends and challenges shaping the CDMO industry as well as the tools helping a leading CDMO meet the growing demand for pediatric formulations and taste-masking solutions.
ORAL DRUG DELIVERY SOLUTIONS
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![iStock-1166584801-OSD-capsule-tablet-oral-solids]( "Improve The Performance Of Your Formulations")
Our platform improves bioavailability, enables higher drug loads, optimizes delivery routes, and enhances formulation performance for small and large molecules across diverse therapeutic applications.
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![GettyImages-1216446418_pellets]( "Multiparticulates For Modified Release Systems")
Multiparticulates enable tailored drug release with improved flexibility, dose accuracy, and patient convenience, leveraging technologies like Diffucaps® for customized profiles including immediate, delayed, extended, and pulsatile delivery.
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![Getty Images-823447656-vector-viral-lab-AAV-cell-development]( "Formulation Strategies For Poorly Soluble Molecules")
As the number of poorly soluble compounds continues to increase in the industry development pipeline, conventional formulation strategies may not be sufficient to achieve acceptable levels of solubility in the gastrointestinal tract and hence absorption into the systemic circulation.
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![Pills tablets capsules]( "Modified-Release Formulation Strategies")
Learn what oral modified-release (MR) dosage forms can offer and why they continue to rise in popularity.
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![Adare-1]( "Manufacturing For Oral Solid Dose Success")
Adare Pharma Solutions provides end-to-end CDMO services for oral solid dose drugs, enabling efficient development, manufacturing, and packaging with advanced technologies and global scale.
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![GettyImages-2156834696-light-bulb-innovation-idea-creativity]( "Battelle: 90 Years Of Innovation")
Battelle, a leading nonprofit in applied science and technology, drives innovation in national security, healthcare, environment, and education while managing research labs and advancing critical discoveries.
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![GettyImages-2176475661 tabet press, pharma manufacturing]( "Streamlining The Generic Combination Device Design Assessment Process")
A new six-phase assessment process simplifies regulatory approval for generic drug-device combination products, reducing costs and timelines while maintaining safety, effectiveness, and substitutability with reference-listed drugs.
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![GettyImages-675683632-lab]( "Formulation And Manufacturing Equipment")
AustinPx offers integrated GMP manufacturing services for oral dosage forms with a full complement of analytical development and testing capabilities.
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![ulab thumb]( "Battelle uLAB")
This comprehensive suite of services encompasses the entire spectrum of user research, starting from the conceptualization of study designs to meticulous data analysis and comprehensive reporting.
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![GettyImages-884796056-solubility-test-pill]( "Pharmaceutical Development")
Developing an optimized formulation tailored to your API nanoparticles is critical to unlocking their full potential.
