ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• High-Throughput Platform Propels Gene Editing Therapy Research

  Explore the potential of polymeric nanoparticles (PNPs) as an alternative to viral vectors. PNPs offer design flexibility, enabling larger payloads, targeted release, and minimized side effects.

• An Elegant Solution For Delivery Of Acid Sensitive Pharmaceuticals

  Sustained release drug delivery products offer effective therapies in the treatment of serious chronic diseases, and their development requires customized solutions with tunable material properties.

• 5 Ways Pre-Filled Syringes Contribute To Better Patient Outcomes

  In our series on pre-filled syringes, we explore five key ways this delivery format is enhancing patient outcomes, not just through the medicine it contains, but through the device design itself.

• Formulation Development From Preclinical To First-In-Human

  A compound with poor biopharmaceutical properties or improper formulation design could lead to a delay in the project or even program termination.

• Vial Containment Systems Based On Elastomer 4031/45 Gray

  Examine the results of two, two-year studies that indicate good container closure integrity performance that can be achieved with stoppers of a given elastomer, independent of configuration.

• Responding To Trends In Prefilled Delivery: Component Assessment And Selection

  Existing plunger technology for PFS was developed for manual injection and does not meet the evolving requirements for drug delivery especially for consistency of injection rate.

• How Devices, Instructions, And Packaging Work Together To Improve Safety

  A medical device's user interface is the entire product system: the device, labeling, packaging, and IFU. These elements are crucial for risk mitigation and must be tested holistically.

• 5 Novel Techniques For Solubility Enhancement

  Thanks to insoluble drug delivery technologies, the practice of reformulating poorly soluble drug products to improve efficacy, patient compliance and safety has now been widely adopted.

• Unlocking New Possibilities For Treating Rare Genetic Diseases

  With over 7,000 rare diseases, the potential for nanomedicine to revolutionize treatment is immense. While polymer nanoparticles hold great promise, several challenges remain.

• Sample Sizes For Performance Testing Of Combination Products, Packaging

  When developing combination products or evaluating primary packaging for drug products one must evaluate the performance of the devices and the packaging to ensure that they are fit-for-purpose.