PLGA-based long-acting injectables drive sustained drug delivery, with advances in generics, depot technologies, and manufacturing expanding patient access and innovation.
- From Vial To Prefilled Syringe: Mastering The Development Transition
- Rethinking The Blueprint For Bone Regeneration: The Next Evolution In Orthobiologics
- Can We Cure Diabetes?
- Reassessing Nanoparticle Immunotoxicity: From Well-Established To Novel Approaches
- Delivery Device Functional Scrutiny: Can You Pass (Without) The Test?
- Red Blood Cell-Based Delivery: Promising Steps Forward
- Stability And Release Testing For Delivery Devices: Waived Or Wanted?
- Microneedles In Drug Delivery: From Bench To Patch
ON-DEMAND WEBINARS
A review of the draft guidance and importance of component selection as it relates to establishing a risk-based approach and the role of the NovaPure product line in component selection.
Review a commercially-ready process capable of reproducing spray-dried dispersions with less manufacturing complexity and environmental impact, and out-designing and outperforming spray drying.
Learn how advanced containment solutions support high-viscosity biologics, improve device compatibility, enhance injection performance, and address evolving drug delivery and patient care challenges.
Various animal models — including non-human primates, rabbits, minipigs, and canines — present benefits and limitations for preclinical studies. Explore the insights to optimize the path to clinical trials.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![GENiSYS-R-full-machine]( "Utilizing Robotic Aseptic Filling Systems To Meet Industry Needs")
Utilizing Robotic Aseptic Filling Systems To Meet Industry NeedsAn aseptic filling and closing machine solution allowed Catalent to reliably process a wide range of both trayed and nested vials for their client product needs.
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![GettyImages-1279969622-self-injector-injection]( "Streamlining The Path To Market For Generic Drug-Device Combinations")
Streamlining The Path To Market For Generic Drug-Device CombinationsDeveloping g-DDCPs is a complex and time-consuming process. By using a risk-based approach, manufacturers can streamline the development process and bring g-DDCPs to market more quickly.
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![AST- Fill-Finish Automation And Robotics]( "Small-Scale Aseptic Filling Technology Considerations")
Small-Scale Aseptic Filling Technology ConsiderationsSmall-scale aseptic filling presents a unique set of challenges. Learn what to look for when evaluating small-scale aseptic filling technology.
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![GettyImages-1291031560-lab-research-computer]( "5 Novel Techniques For Solubility Enhancement")
5 Novel Techniques For Solubility EnhancementThanks to insoluble drug delivery technologies, the practice of reformulating poorly soluble drug products to improve efficacy, patient compliance and safety has now been widely adopted.
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![GettyImages-872019514-dna-gene-teach]( "Container Closure Integrity Evaluation For Cell And Gene Therapies")
Container Closure Integrity Evaluation For Cell And Gene TherapiesWith the growth of gene and cell therapies, there is an increased need to characterize container closure systems at the low temperatures experienced during their lifecycles.
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![GettyImages-1328085510-patient-child-doctor-pediatric]( "Combining Patient Centricity And Commercial Viability In Pediatric Product Development")
Combining Patient Centricity And Commercial Viability In Pediatric Product DevelopmentMedication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
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![GettyImages-851771510-eye-futuristic-scanning]( "Ophthalmic Drug Delivery")
Ophthalmic Drug DeliveryExplore the challenges to effective delivery of drugs to the eye, intricacies of ophthalmic drug delivery, and advantages of nanoparticles as an enabling technology for ocular drug-delivery systems.
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![GettyImages-1027752634]( "Selecting An Alternative Coating Technology To Silicone Oil For Prefillable Syringes")
Selecting An Alternative Coating Technology To Silicone Oil For Prefillable SyringesThe challenges of silicone-oil lubrication and the growing trend for more viscous, protein-based drugs are now leading pharma and biotech companies to investigate alternative solutions.
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![GettyImages-1353123922-doctor-patient]( "Why 'Off-The-Shelf' Devices Do Not Circumvent Design Controls")
Why 'Off-The-Shelf' Devices Do Not Circumvent Design ControlsUtilizing off-the-shelf (OTS) devices for drug delivery can offer significant advantages to development programs in timeline and risk mitigation. Understand the design control responsibilities of a sponsor when using OTS devices.
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![Syringes GettyImages-171324030]( "5 Ways Pre-Filled Syringes Contribute To Better Patient Outcomes")
5 Ways Pre-Filled Syringes Contribute To Better Patient OutcomesIn our series on pre-filled syringes, we explore five key ways this delivery format is enhancing patient outcomes, not just through the medicine it contains, but through the device design itself.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
Fran offers keen industry and technical insights exclusively on Drug Delivery Leader.
DELIVERED BY DEGRAZIO
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![Delivered _by _DeGrazio_Logo_Color_2]( "From Vial To Prefilled Syringe: Mastering The Development Transition")
From Vial To Prefilled Syringe: Mastering The Development TransitionIn this article, Fran DeGrazio discusses the opportunities, challenges, and benefits for biopharmaceutical product developers in transitioning from vial-based to prefilled syringe (PFS) delivery approaches. She lays out key differences and added complexities in areas such as device functionality, risk management, regulatory pathways, use of materials, lifecycle management, and organizational alignment.
FREE EBOOK: COMBINATION PRODUCTS
Combination products provide significant avenues for increasing patient adherence and overall efficacy. This collection outlines the opportunity and identifies strategies for gaining regulatory approval.
