We caught up with Davinder Ramsingh, MD, to talk about the potential of using low-intensity focused ultrasound (LIFU) to open the blood–brain barrier.
- Beyond GalNAc: Reengineering siRNA For Extrahepatic Delivery
- Engineering CAR T Cells With mRNA-LNPs: Applying Oncology Learnings To Allergic Diseases
- The Future Of Cancer Drug Discovery Is Targeted Immune Activation
- Part 4 cGMP Summaries For Combination Products: Uncovering FDA Expectations
- Unpacking The FDA Draft Guidance On Container Closure Systems
- Turning A Historically Limited Modality Into A Respiratory Drug Opportunity
- Why Delivery Is Defining The Next Era Of Neuromuscular Therapeutics
- Inquiries In Inhalation, Part 2: Having A Nose For Innovation
ON-DEMAND WEBINARS
The simultaneous spray drying of multiple ingredients is a powerful technique for making inhaled products with multiple actives. Examine how novel techniques can make these products a reality.
Various animal models — including non-human primates, rabbits, minipigs, and canines — present benefits and limitations for preclinical studies. Explore the insights to optimize the path to clinical trials.
Developing new delivery routes is essential for creating more effective treatments. Nanoforming enables new routes to simplify dosing, enhance patient comfort, and reduce healthcare costs.
We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![GettyImages-1293772957-scientist-laboratory-computer-drug-development]( "Solving For The Future Of Drug Delivery")
Solving For The Future Of Drug DeliveryNext-gen therapeutics require equally advanced delivery systems—localized, personalized, and precise—to ensure efficacy, safety, and scalability. Delivery is now a central driver of innovation.
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![iStock-1087219198-lab-computer-cleanroom-research-development-production]( "Spray Drying: Advantages And Disadvantages")
Spray Drying: Advantages And DisadvantagesWhen it comes to formulation development, pharmaceutical spray drying is one of the most versatile solutions. Review a detailed look at the steps involved in spray drying and the benefits and downsides.
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![02 West]( "Essential Drug Delivery Outputs For Devices To Deliver Drugs, Biologics")
Essential Drug Delivery Outputs For Devices To Deliver Drugs, BiologicsAll future submissions are expected to align with FDA's draft guidance that clarifies the agency's expectations for establishing, evaluating, and controlling Essential Drug Delivery Output (EDDO) requirements.
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![West-Vol 7-Blog]( "FAQs On The Revised EU GMP Annex 1: Volume 7")
FAQs On The Revised EU GMP Annex 1: Volume 7Modernize your sterile manufacturing approach. Explore essential insights on contamination control strategies, risk management, and barrier technologies to ensure full regulatory alignment.
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![GettyImages-1441662840-lab-team-communication-collaboration]( "4 Most Common Reasons For Medical Device Material Failures")
4 Most Common Reasons For Medical Device Material FailuresMaterial failures in medical devices can have severe consequences for companies. By implementing a proactive design framework , companies can significantly reduce these risks and the associated costs.
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![GettyImages-627023398 clinical lab]( "Navigating PFAS \"Forever Chemicals\" In Medical Devices - What's On The Horizon")
Navigating PFAS "Forever Chemicals" In Medical Devices - What's On The HorizonGain an understanding of PFAS, their properties, environmental impact, health risks, and regulatory challenges, focusing on the specific implications for the medical device industry.
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![Evonk DA-HealthCare Tablets 13 5 2019 Macro mas-foto_100]( "An Insoluble Problem? Oral Drug Solubility With Functional Polymers")
An Insoluble Problem? Oral Drug Solubility With Functional PolymersReview the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility and common questions on the topic.
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![GettyImages-1306440102-sterile-injectable-syringe]( "The Growth Of Sterile Injectables")
The Growth Of Sterile InjectablesLearn why partnering with a manufacturer capable of delivering flexible aseptic fill-finish solutions for any size production run is essential for delivering products to patients safely and efficiently.
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![AST- ASEPTiCell ScreenShot 16]( "The Future Of CDMOs: Aseptic Filling Solutions For Growth And Innovation")
The Future Of CDMOs: Aseptic Filling Solutions For Growth And InnovationThe rapid rise of highly targeted cell and gene treatments requiring small batch production necessitates a new path forward for biologics manufacturing and directly impacts the CMO/CDMO landscape.
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![Wooden blocks PFAS-GettyImages-2145498657]( "PFAS In Medical Devices: Expert Insights On Frequently Asked Questions")
PFAS In Medical Devices: Expert Insights On Frequently Asked QuestionsWatch to learn more about PFAs in medical devices, covering environmental concerns, health risks, testing, alternatives and management strategies with Shalene Thomas of Battelle.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
Fran offers keen industry and technical insights exclusively on Drug Delivery Leader.
DELIVERED BY DEGRAZIO
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![Delivered _by _DeGrazio_Logo_Color_2]( "Unpacking The FDA Draft Guidance On Container Closure Systems")
Unpacking The FDA Draft Guidance On Container Closure SystemsIn this article, Fran DeGrazio reflects on the significance of the FDA Draft Guidance on Container Closure Systems, the first update since 1999. DeGrazio places the CCS draft guidance in the current context of science-based and risk-based product development for combination products and other injectable drug product delivery systems. She also addresses the integration of CCS guidance into the development organization’s QMS (Quality Management System).
FREE EBOOK
Why Human Factors Are Critical To Drug Delivery Device Success
In today’s highly competitive biopharma market, successful therapies prioritize the patient experience. Increasingly, patients expect to receive advanced therapies at home or in decentralized care settings, which require delivery methods that are easy to use and comfortable.
This collection explores how drug delivery teams can incorporate patient-centricity across development, from early human factors strategies to modality selection, ensuring safe, effective therapies that translate to real-world care.
