BCS Class IV drugs have low solubility and permeability. Oral nanoparticles can overcome both barriers, offering a more effective and tunable oral delivery strategy.
- AI: The Inflection Point In Retinal Drug Discovery, Development, And Delivery
- Reformulating An In-Clinic IV To At-Home Injection Puts Patients At The Center
- AI, Digitalization, And In Vivo Programming Redefine Cell And Gene Therapy
- Minding The Gap: Submission Strategies For Combined Use Combination Products
- Advances In Precision Delivery In CNS Oncology
- Drug-Device Combination Products: 4 Evolving Platforms For 2026
- A Case Study: Control Strategies For A Multi-Dose Pen Injector
- Control Strategies For Injectable Drug Delivery Combination Products
ON-DEMAND WEBINARS
Developing new delivery routes is essential for creating more effective treatments. Nanoforming enables new routes to simplify dosing, enhance patient comfort, and reduce healthcare costs.
Discover an advancement in the prefillable syringe market, uniquely integrating the syringe barrel, plunger, and needle shield/tip cap into a fully harmonized, verified system from a single supplier.
If you are in the process of developing a complex or sensitive injectable drug, learn about containment solutions to mitigate your risks and help you get your drug to the patient faster.
The simultaneous spray drying of multiple ingredients is a powerful technique for making inhaled products with multiple actives. Examine how novel techniques can make these products a reality.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
-
![Evonk DA-HealthCare Tablets 13 5 2019 Macro mas-foto_100]( "An Insoluble Problem? Oral Drug Solubility With Functional Polymers")
An Insoluble Problem? Oral Drug Solubility With Functional PolymersReview the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility and common questions on the topic.
-
![BO 2 - GC_App_^CZ vial with stopper and seal stack up]( "Bringing A Biosimilar For Oncology To Market: Injectable Packaging From Early Development To Commercialization")
Bringing A Biosimilar For Oncology To Market: Injectable Packaging From Early Development To CommercializationWhile in their early-stage development of a mAb biosimilar for oncology treatment, a large biopharmaceuticals company sought a packaging recommendation: a stopper to maintain high-quality standards.
-
![GettyImages-1311641109-capsule-tablet-pill-OSD-oral-solid]( "Capsule Formulation Development: From Dosage Forms To Filling")
Capsule Formulation Development: From Dosage Forms To FillingCapsules are tasteless and easy to take, offer streamlined development timelines, and simplicity of manufacturing. Discover capsule formulation development and the benefits of capsule dosage forms.
-
![West-MDO 1 - GC_APP_Assembled and Unassembled Vials V1]( "FAQs On The Revised EU GMP Annex 1: Volume 1")
FAQs On The Revised EU GMP Annex 1: Volume 1The revised GMP Annex 1 guidelines emphasize quality risk management, enhanced environmental monitoring, and data integrity, which aim to minimize contamination and ensure patient safety.
-
![Computational Science: Disruption In Biopharma Discovery]( "Formulation Research Strategy For Discovery- Stage New Drug Candidates")
Formulation Research Strategy For Discovery- Stage New Drug CandidatesEarly stage formulation studies, which should support the emerging target product profile, will often yield important experimental results to aid subsequent development of clinically relevant dosage forms.
-
![iStock-1313401849-syringe]( "Overcome Common Pre-Filled Syringe Challenges Through Partnership")
Overcome Common Pre-Filled Syringe Challenges Through PartnershipThe pre-filled syringe space is one of the fastest growing pharma sectors, offering greater patient safety and lower manufacturing costs. But pre-filled doesn’t translate to easily filled; there are particular obstacles to overcome.
-
![GettyImages-1191463139-lab-test-tube-experiment]( "Steps To Overcome Challenges Associated With Biologic Formulation Development")
Steps To Overcome Challenges Associated With Biologic Formulation DevelopmentExplore guidance on the challenges posed by biologics, including overcoming degradation, establishing a stress test process, and the value of lipid nanoparticles (LNPs) and polymeric nanoparticles (NPs).
-
![IPC-filling]( "Aseptic Filling And Processing Considerations For Biosimilars")
Aseptic Filling And Processing Considerations For BiosimilarsOne of the most intriguing, high-stakes aspects of R&D is the realm of biosimilars. Explore the challenges of biosimilar production as well as aseptic processing considerations for biosimilars.
-
![West-Labs 093_ASE-0111]( "Establishing And Safeguarding Shelf Life In Combination Products")
Establishing And Safeguarding Shelf Life In Combination ProductsEstablishing combination product shelf life requires aligning stability. Holistic, data-driven stability studies ensure product function, safety, and label claims through the entire supply chain.
-
![West]( "Design And Packaging Advantages For Cell And Gene Therapy Drugs")
Design And Packaging Advantages For Cell And Gene Therapy DrugsWith the increasing demand for cell and gene therapies, Crystal Zenith nested vials can help the biopharma industry overcome the challenges of scaling up manufacturing and logistics.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
Fran offers keen industry and technical insights exclusively on Drug Delivery Leader.
DELIVERED BY DEGRAZIO
-
![Delivered _by _DeGrazio_Logo_Color_2]( "6 Packaging And Delivery Challenges For Biologic Therapies")
6 Packaging And Delivery Challenges For Biologic TherapiesIn this article, Fran DeGrazio identifies six aspects of biologics-based therapy packaging and delivery that, if addressed, may help to ensure successful product development and lifecycle management. They include 1) chemical compatibility with device functionality, 2) long-acting formulations, 3) product stability, 4) primary packaging and device integration, 5) cold storage, and 6) higher concentrations and viscosities.
FREE EBOOK: COMBINATION PRODUCTS
Combination products provide significant avenues for increasing patient adherence and overall efficacy. This collection outlines the opportunity and identifies strategies for gaining regulatory approval.
