We caught up with Davinder Ramsingh, MD, to talk about the potential of using low-intensity focused ultrasound (LIFU) to open the blood–brain barrier.
- Beyond GalNAc: Reengineering siRNA For Extrahepatic Delivery
- Engineering CAR T Cells With mRNA-LNPs: Applying Oncology Learnings To Allergic Diseases
- The Future Of Cancer Drug Discovery Is Targeted Immune Activation
- Part 4 cGMP Summaries For Combination Products: Uncovering FDA Expectations
- Unpacking The FDA Draft Guidance On Container Closure Systems
- Turning A Historically Limited Modality Into A Respiratory Drug Opportunity
- Why Delivery Is Defining The Next Era Of Neuromuscular Therapeutics
- Inquiries In Inhalation, Part 2: Having A Nose For Innovation
ON-DEMAND WEBINARS
Explore how our on-body delivery system supports high-volume biologic delivery by balancing usability, patient needs, and sustainability through research-driven design.
Discover how these groundbreaking Oral GLP-1 Analogs therapies are reshaping obesity management and addressing key challenges in formulation and delivery.
‘Brick dust’ compounds require additional steps if spray drying is to yield a commercially attractive process. Explore three enabling technologies designed to improve drug solubility in organic solvents for spray drying.
See how PBPK models combined with custom and off-the-shelf in vitro tools and solubility enhancement expertise can reduce the need for drug product reformulation or repeated preclinical or clinical studies.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![Image 4]( "Minimizing Particulate Risk: Designing For Control")
Minimizing Particulate Risk: Designing For ControlEffective particulate control in aseptic fill/finish operations requires coordinated design decisions spanning airflow configuration, static mitigation, transport mechanisms, and closure handling.
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![GettyImages-1309471798 respiratory]( "Outlining The Trends And Challenges In The Inhaled Drug Delivery Market")
Outlining The Trends And Challenges In The Inhaled Drug Delivery MarketExplore the latest trends and solutions in inhaled drug delivery, with a focus on overcoming dry powder formulation challenges to advance next-generation therapeutics.
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![Scientists Mixing Solution In Lab GettyImages-1443286944]( "Formulation Development For Injectables")
Formulation Development For InjectablesA uniquely modified cyclodextrin is emerging as a versatile and indispensable tool for development. Explore how the right formulation approach can enhance drug delivery and improve patient outcomes.
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![istock1087218874-lab-drug]( "Lyophilization vs. Liquid Formation: Why Lyo Offers Advantages")
Lyophilization vs. Liquid Formation: Why Lyo Offers AdvantagesLyophilization offers some alluring advantages in today’s complex market, but its challenges require innovation and expertise to surmount.
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![GettyImages-1219894397 Medical Device Manufacturing]( "A Solvent-Free, Fusion-Based ASD Manufacturing Process")
A Solvent-Free, Fusion-Based ASD Manufacturing ProcessExplore a solvent-free alternative for the production of amorphous solid dispersions (ASDs) that not only improves manufacturability but also reduces the carbon footprint of ASD manufacturing.
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![GettyImages-2086161977-blister-packaging-liquid-medical-medicine]( "The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric Solutions")
The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric SolutionsPharmaceutical packaging must evolve alongside drug development to ensure stability, safety, and regulatory adherence, utilizing innovative designs to improve therapeutic outcomes and patient accessibility.
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![GettyImages-893884884-lab-research-team]( "Considerations In Development & Manufacturing Of Complex Injectables For Early Phase Studies")
Considerations In Development & Manufacturing Of Complex Injectables For Early Phase StudiesA niche CDMO, with specialized technologies in complex injectable development, will have greater flexibility for successful manufacture of complex injectables in early phase development of therapeutic drugs.
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![Singota-DSC03385]( "Which Testing Does An Effective Certificate Of Analysis Include?")
Which Testing Does An Effective Certificate Of Analysis Include?Discerning mandatory testing from supplemental testing for early-stage injectable or IV-infusion therapies streamlines CoA creation and promotes regulatory compliance.
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![GettyImages-1465073112-tablet-pill-OSD]( "Streamline Early-Stage Development To Reach The Clinic Faster")
Streamline Early-Stage Development To Reach The Clinic FasterEarly-stage development is an iterative process, continuously generating new data and insights to optimize the product based on emerging knowledge.
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![West-Ready Pack_006 LR]( "Extractables And Leachables: A Critical Part Of CCS Under EU GMP Annex 1")
Extractables And Leachables: A Critical Part Of CCS Under EU GMP Annex 1Managing chemical migration from packaging and process equipment is essential to protect patient safety, maintain drug stability, and ensure regulatory compliance.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
Fran offers keen industry and technical insights exclusively on Drug Delivery Leader.
DELIVERED BY DEGRAZIO
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![Delivered _by _DeGrazio_Logo_Color_2]( "Unpacking The FDA Draft Guidance On Container Closure Systems")
Unpacking The FDA Draft Guidance On Container Closure SystemsIn this article, Fran DeGrazio reflects on the significance of the FDA Draft Guidance on Container Closure Systems, the first update since 1999. DeGrazio places the CCS draft guidance in the current context of science-based and risk-based product development for combination products and other injectable drug product delivery systems. She also addresses the integration of CCS guidance into the development organization’s QMS (Quality Management System).
FREE EBOOK
Why Human Factors Are Critical To Drug Delivery Device Success
In today’s highly competitive biopharma market, successful therapies prioritize the patient experience. Increasingly, patients expect to receive advanced therapies at home or in decentralized care settings, which require delivery methods that are easy to use and comfortable.
This collection explores how drug delivery teams can incorporate patient-centricity across development, from early human factors strategies to modality selection, ensuring safe, effective therapies that translate to real-world care.
