Reformulation improves adherence by reducing pill burden and side effects, enhancing real-world usability and align therapies with diverse patient needs.
- Regulatory Attention To Human Factors: How Much Is There?
- Gaining An Edge In GLP-1 Production
- Transendocardial Cell Delivery In Post‑Acute Myocardial Infarction
- Where Drug Delivery Falls Short And What The Industry Should Do Next
- BCS Class IV: Rescuing Hard To Deliver Molecules With Nanoformulation
- Patient-Centric Drug Delivery: Do Possible And Preferable Always Align?
- Expanding The IV → SC Framework: What Reformulation Really Means
- AI: The Inflection Point In Retinal Drug Discovery, Development, And Delivery
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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Lyophilization vs. Liquid Formation: Why Lyo Offers Advantages
Lyophilization offers some alluring advantages in today’s complex market, but its challenges require innovation and expertise to surmount.
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Drug Formulation Development: Quick Reference Guide
This guide shares the steps involved in formulation development, considerations during formulation, and how partnering with an experienced CDMO can lead to a successful commercial product.
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PHI And Medical Devices: What Device Manufacturers Need To Know
Connected medical devices must treat Protected Health Information (PHI) protection as integral to patient safety and compliance. Understand the data flows and HIPAA requirements to design security.
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Spray Drying: Advantages And Disadvantages
When it comes to formulation development, pharmaceutical spray drying is one of the most versatile solutions. Review a detailed look at the steps involved in spray drying and the benefits and downsides.
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Navigating PFAS "Forever Chemicals" In Medical Devices - What's On The Horizon
Gain an understanding of PFAS, their properties, environmental impact, health risks, and regulatory challenges, focusing on the specific implications for the medical device industry.
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Engineering Approaches To Respiratory Drug Delivery
Explore the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.
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Solutions For Accelerated Pharmaceutical Development
Explore an integrated service package designed to simplify and accelerate the development pathway, even for APIs with challenging properties such as low aqueous solubility and poor bioavailability.
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Accelerate Development Of Enabled Formulations For Poorly Soluble Drugs
Explore how a platform integrating drug substance, drug product, and clinical testing within a single organization accelerates development and reduces costs, helping deliver positive outcomes earlier.
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Accelerate LNP Manufacturing With Automated Process Development
Manual LNP formulation introduces process variability that threatens particle quality and yield. As programs scale toward clinical production, maintaining strict control over CQAs becomes essential.
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Considerations In Development & Manufacturing Of Complex Injectables For Early Phase Studies
A niche CDMO, with specialized technologies in complex injectable development, will have greater flexibility for successful manufacture of complex injectables in early phase development of therapeutic drugs.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
DELIVERED BY DEGRAZIO
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6 Packaging And Delivery Challenges For Biologic Therapies
In this article, Fran DeGrazio identifies six aspects of biologics-based therapy packaging and delivery that, if addressed, may help to ensure successful product development and lifecycle management. They include 1) chemical compatibility with device functionality, 2) long-acting formulations, 3) product stability, 4) primary packaging and device integration, 5) cold storage, and 6) higher concentrations and viscosities.

