ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• How To Leverage Modeling And Simulation In The Candidate Development Stage

  Modeling and simulation provides another way to predict the clinical performance of a molecule, based on a robust and holistic approach, before investing the required time and money.

• Simultaneous Spray Drying For Innovative Dry Powder Inhaler Combination Formulations

  Dr. Kimberly Shepard, a principal R&D engineer at Lonza, offered insights on recent innovations pioneered in spray drying. Shepard also discussed spray drying technologies capable of combining small-molecule APIs with biotherapeutic molecules.

• Delivering Macromolecules: Challenges Associated With The Delivery Of Biologic Drugs

  Developers need to look beyond the formulation of a stable drug all the way to patient compliance. Numerous pitfalls exist along the journey to bring a biologic combination product to market. This integrated solutions program can help you simplify the journey.

• Benefits Of Microparticle Technology For Oral Drug Solubility Enhancement

  Spray-dried dispersions, hot-melt extrusion, and solubilizing excipients are common solubility enhancement techniques, but new developments to maximize amorphous solid dispersion benefits are needed.

• Maintaining Superior Viral Vector Recovery In Cell And Gene Therapy Applications

  A study assessing the stability of vials aimed to determine if the vial material had any influence on the viral titer and particle counts of the AAV serotypes.

• Self-Injection Of Biologics Made Easy

  Ready-to-Use (RTU) 3mL cartridge-based, single-use Pen Devices are specifically designed to ensure consistency of delivery for high-volume, high-viscosity injectable drug delivery systems.

• A Lifecycle Management Strategy For Sterile Injectables

  Gain insight into the benefits and challenges of transferring a therapeutic compound from one aseptic injectable format to another.

• Reduce Costs And Improve Adherence For Self-Administration Of Biologics

  There is a growing trend toward wearable injectors for bolus delivery in order to help improve adherence and lower the costs of therapy. 

• How Dermal Delivery Platforms Are Transforming Tomorrows For Patients

  Skin delivery platforms expand therapies by boosting convenience, stability, and adherence. Integrated formulation, device, and manufacturing development is key to confidently scale.

• Delivering Market Success For Pharma Partners From Concept To Patient

  The development of drug delivery devices that are innovative, intuitive, patient friendly, and patient safe must address certain areas of concern that are particular to both biologic and biosimilar therapies.