PLGA-based long-acting injectables drive sustained drug delivery, with advances in generics, depot technologies, and manufacturing expanding patient access and innovation.
- From Vial To Prefilled Syringe: Mastering The Development Transition
- Rethinking The Blueprint For Bone Regeneration: The Next Evolution In Orthobiologics
- Can We Cure Diabetes?
- Reassessing Nanoparticle Immunotoxicity: From Well-Established To Novel Approaches
- Delivery Device Functional Scrutiny: Can You Pass (Without) The Test?
- Red Blood Cell-Based Delivery: Promising Steps Forward
- Stability And Release Testing For Delivery Devices: Waived Or Wanted?
- Microneedles In Drug Delivery: From Bench To Patch
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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Key Financial Considerations For Phase II Clinical Injectable Drug Manufacturing
This article highlights the importance of scalability and flexibility in the choice of an early-stage manufacturing strategy and how that decision impacts financial outcomes for a drug development program.
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Bilayer Tablet Manufacturing: An Overview
Bilayer tablets offer a number of benefits for patient care; understanding the challenges that accompany their formulation is key to enabling their successful commercialization.
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Snapshot Of The Parenteral Drug Delivery Market
Growth in the development of parenteral drugs is driving demand for advanced drug delivery devices such as prefilled syringes, autoinjectors, and pen-injectors, growing segments in fill-finish manufacturing.
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How Subcutaneous Delivery Can Help Patients Manage Chronic Conditions
Read more about how to improve your patients’ outcomes, avoid costly delays to launch, and provide a better return on investment.
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Containment Solutions To Help Emerging Biologic Companies
Set up your small company for long-term success using packaging containment offerings and services to help mitigate risks and speed up your time to market.
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Meeting The Growing Demand For Pre-Filled Syringes
The market for pre-filled syringes is growing rapidly. Learn more about the benefits for consumers, providers, and manufacturers, and the importance of partnering with a reliable fill finish facility.
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Best Practices For Ensuring Quality In Biologic Products
New biologic therapies have new challenges in their packaging and delivery systems because of their complexities, higher stability risks, and larger sizes.
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Early Decisions To De-Risk The Transition To Combination Products
The injectable product development landscape is changing, and the pressure to accelerate timelines remains constant. What can you do to overcome all the uncertainty and risk?
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Supporting Complex Manufacturing For Liquid And Lyophilized Drug Products
Aseptic fill and finish operations gain efficiency and precision with modular isolator technology, inline weight checks, and lyophilization, which are ideal for mRNA-LNPs and other sensitive modalities.
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Elastomer Plungers With Barrier Film For COVID-19 Vaccines
Minimize the risks of accelerated drug development processes and the potential use of new vaccine platform technologies with the use of an elastomer plunger laminated with FluroTec™ barrier film.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
DELIVERED BY DEGRAZIO
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From Vial To Prefilled Syringe: Mastering The Development Transition
In this article, Fran DeGrazio discusses the opportunities, challenges, and benefits for biopharmaceutical product developers in transitioning from vial-based to prefilled syringe (PFS) delivery approaches. She lays out key differences and added complexities in areas such as device functionality, risk management, regulatory pathways, use of materials, lifecycle management, and organizational alignment.

