Next-generation drug delivery pairs science with usability, solving adherence by simplifying treatment, aligning patient behavior, and improving poorly tolerated therapies.
- Expanding The IV → SC Framework: What Reformulation Really Means
- AI: The Inflection Point In Retinal Drug Discovery, Development, And Delivery
- Reformulating An In-Clinic IV To At-Home Injection Puts Patients At The Center
- AI, Digitalization, And In Vivo Programming Redefine Cell And Gene Therapy
- Minding The Gap: Submission Strategies For Combined Use Combination Products
- Advances In Precision Delivery In CNS Oncology
- Drug-Device Combination Products: 4 Evolving Platforms For 2026
- A Case Study: Control Strategies For A Multi-Dose Pen Injector
ON-DEMAND WEBINARS
What if a formulation that removed the need for cold chain distribution was possible? Explore the formulation of vaccines and manufacturing considerations for dry powder inhaled vaccines.
By reducing the size of drug particles, nanoforming offers new opportunities — from increased bioavailability to sustained drug delivery. Discover the potential benefits supported by case studies.
Using volatile processing aids to increase drug solubility in more environmentally friendly solvents, like methanol, reduces the amount of solvent required to manufacture amorphous solid dispersions (ASDs).
Discover how these groundbreaking Oral GLP-1 Analogs therapies are reshaping obesity management and addressing key challenges in formulation and delivery.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![West-Vials Glamour V9]( "Long-Term Container Closure Integrity Testing Of Vial-Stopper-Seal Combinations")
Long-Term Container Closure Integrity Testing Of Vial-Stopper-Seal CombinationsThe study was designed to investigate CCI over a period of 24 months at ambient, ultra-low and cryogenic temperatures for serum-stopper samples and at ambient temperature for lyo-stopper samples.
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![GettyImages-1219894348-lab-cleanroom-PPE]( "Driving Sustainability In Spray Drying Through Enabling Technologies")
Driving Sustainability In Spray Drying Through Enabling TechnologiesBy transitioning to alternative solvents or leveraging process aids, the challenges associated with the use of these chemicals can be addressed, helping create a sustainable, greener footprint.
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![Evonk DA-HealthCare Tablets 13 5 2019 Macro mas-foto_100]( "An Insoluble Problem? Oral Drug Solubility With Functional Polymers")
An Insoluble Problem? Oral Drug Solubility With Functional PolymersReview the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility and common questions on the topic.
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![Artificial Intelligence, Technology, Robot, Futuristic, Data Science, Data Analytics, AI-GettyImages-1480912336]( "AI: The New Partner In Medical Device Development")
AI: The New Partner In Medical Device DevelopmentInvolving users in the development process and staying informed about regulatory policies can help ensure AI-powered devices meet the needs of patients and healthcare professionals.
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![SIS_SelfDose_042 _1252_RGB]( "How Subcutaneous Delivery Can Help Patients Manage Chronic Conditions")
How Subcutaneous Delivery Can Help Patients Manage Chronic ConditionsRead more about how to improve your patients’ outcomes, avoid costly delays to launch, and provide a better return on investment.
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Gaps In Reconstitution Process Filled By Water-For-Injection Syringe
The recent rise in biopharmaceutical drugs has sparked renewed interest in lyophilization as a way to bring injectable biologics and other drugs to market more quickly.
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![iStock-1319077865-lab-team-computer-research]( "Amorphous Formulations For Insoluble Drugs: Rational Design & Practical Approaches On Formulation Screening & Development")
Amorphous Formulations For Insoluble Drugs: Rational Design & Practical Approaches On Formulation Screening & DevelopmentThe issues associated with amorphous formulations include solid state stability, chemical stability, reproducibility of API manufacturing, impurity of API, in vitro in vivo performance, process and scale-up.
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![iStock-1268181219-glass-vial-packaging-sterile]( "Container Closure Integrity: A Risk-Based Approach")
Container Closure Integrity: A Risk-Based ApproachContainer closure integrity is essential to protecting drug product and satisfying regulatory agencies. A risk-based approach enables creation of a robust data file for timely approval of regulatory applications.
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![Wooden blocks PFAS-GettyImages-2145498657]( "PFAS In Medical Devices: Expert Insights On Frequently Asked Questions")
PFAS In Medical Devices: Expert Insights On Frequently Asked QuestionsWatch to learn more about PFAs in medical devices, covering environmental concerns, health risks, testing, alternatives and management strategies with Shalene Thomas of Battelle.
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![GettyImages-1156884561-fill-finish]( "Key Considerations For Selecting Flexible Fillers")
Key Considerations For Selecting Flexible FillersFlexible fillers are beneficial to drug developers looking for lifecycle management of their drug products. Explore key considerations for selecting flexible fill/finish manufacturing technologies.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
Fran offers keen industry and technical insights exclusively on Drug Delivery Leader.
DELIVERED BY DEGRAZIO
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![Delivered _by _DeGrazio_Logo_Color_2]( "6 Packaging And Delivery Challenges For Biologic Therapies")
6 Packaging And Delivery Challenges For Biologic TherapiesIn this article, Fran DeGrazio identifies six aspects of biologics-based therapy packaging and delivery that, if addressed, may help to ensure successful product development and lifecycle management. They include 1) chemical compatibility with device functionality, 2) long-acting formulations, 3) product stability, 4) primary packaging and device integration, 5) cold storage, and 6) higher concentrations and viscosities.
FREE EBOOK: COMBINATION PRODUCTS
Combination products provide significant avenues for increasing patient adherence and overall efficacy. This collection outlines the opportunity and identifies strategies for gaining regulatory approval.
