ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Streamlining Primary Container And Device Selection With Predictive Calculations

  Expolore a theoretical approach to complement experimental approaches to more quickly select a packaging and delivery system for your drug product.

• 10 Ways To Align Your Medical Device With Human Factors Industry Best Practices

  Discover how patient-centric design principles can improve the development of medical devices. By focusing on user needs and behaviors, manufacturers can ensure that products align with expectations.

• How To Achieve Precise And Flexible Dosing With Multiparticulates

  For orally delivered medicines, developers often must balance a drug’s “curb appeal” — its specific delivery mechanism, taste, ease of administration, and convenience — with safety and efficacy.

• Recent Innovations And Enhancements To Pharmaceutical Spray Drying

  Finding alternative solvent approaches could allow for lower volumes of less toxic solvents, significantly improving both the environmental and human health implications of new drugs produced.

• Application Of Nano-Emulsion Technology To Address Unmet Medical Needs: A Case Study Of Clopidogrel IV By 505(b)(2) Pathway

  Review a process where the insoluble and unstable free-base form of clopidogrel is converted to a form with acceptable drug loading and is protected from chemical degradation.

• Leveraging Integration At Each Phase Of A Drug Delivery System Project

  By forging deeper partnerships with customers, the full depth and breadth of our knowledge, experience and competencies can bring benefits at multiple levels. See how an integrated offering helps at each phase of a drug delivery system project.

• Formulation Development Strategy For Early Phase Human Studies

  Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.

• Sterile Injectable Therapies: Revolutionizing Lifecycle Management

  The right balance of technical understanding, logistics, regulatory guidelines, and knowledge about product stability and quality is crucial for capitalizing on the benefits of shifting delivery formats.

• Solid Form Strategies For Increasing Oral Bioavailability

  Optimizing a drug’s solid form can improve its solubility and bioavailability when further molecular modifications are prohibitive.

• Importance Of Assessing Mannitol Crystallinity In Lyophilized Drug Products

  Drug product stability may be seriously compromised if mannitol completes crystallization during storage rather than during the freezing or annealing step in the lyophilization process.