Cell therapy success depends on a durable implantation environment, making delivery and sustainability central to efficacy and functional outcomes.
- Human Factors: A Key Factor In Regulatory Approvals
- Regulatory Attention To Human Factors: How Much Is There?
- Gaining An Edge In GLP-1 Production
- Transendocardial Cell Delivery In Post‑Acute Myocardial Infarction
- Where Drug Delivery Falls Short And What The Industry Should Do Next
- BCS Class IV: Rescuing Hard To Deliver Molecules With Nanoformulation
- Patient-Centric Drug Delivery: Do Possible And Preferable Always Align?
- Expanding The IV → SC Framework: What Reformulation Really Means
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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Reduce Costs And Improve Adherence For Self-Administration Of Biologics
There is a growing trend toward wearable injectors for bolus delivery in order to help improve adherence and lower the costs of therapy.
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Accelerating The Development Of Oncology Medicines
Oncology drug development has seen a significant shift in focus, as molecule chemistries and drug technologies have improved. Explore five areas for consideration and the potential emerging solutions.
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Making The Right Choice For Multiparticulate Modified Release Dosage Forms
Wurster processing is a versatile pharmaceutical development and manufacturing technique for multiparticulates in modified release dosage forms. Understand if it's the right method for your modified-release project.
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Key Considerations For Selecting Flexible Fillers
Flexible fillers are beneficial to drug developers looking for lifecycle management of their drug products. Explore key considerations for selecting flexible fill/finish manufacturing technologies.
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Reducing Environmental Impact At All Stages Of The Medicine Journey
Explore how utilizing technologies like AI and digital twinning can inform decision-making at the R&D stage and how to optimize the delivery of the final drug product to patients with greener logistics.
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Spray Drying: Advantages And Disadvantages
When it comes to formulation development, pharmaceutical spray drying is one of the most versatile solutions. Review a detailed look at the steps involved in spray drying and the benefits and downsides.
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Device Design For Usability And Risk Reduction
Growing use of large‑volume subcutaneous therapies is increasing demand for wearable injectors that reduce user error, simplify preparation, and enhance safety through human‑factors‑focused design.
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Establishing And Safeguarding Shelf Life In Combination Products
Establishing combination product shelf life requires aligning stability. Holistic, data-driven stability studies ensure product function, safety, and label claims through the entire supply chain.
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New Perspectives On Accelerating Genetic Nanomedicines Through The Regulatory Pathway
Discover how regulatory bodies are adopting a risk-based approach to address the unique challenges of genetic nanomedicines, and stakeholder engagement is essential.
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Improved Biomanufacturing Processes And Drug Product Stability
Improve upstream media for bioavailability and foam stability, downstream buffers for purification, and the formulation and final fill drug product stability with this highly interdisciplinary process.
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
DELIVERED BY DEGRAZIO
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6 Packaging And Delivery Challenges For Biologic Therapies
In this article, Fran DeGrazio identifies six aspects of biologics-based therapy packaging and delivery that, if addressed, may help to ensure successful product development and lifecycle management. They include 1) chemical compatibility with device functionality, 2) long-acting formulations, 3) product stability, 4) primary packaging and device integration, 5) cold storage, and 6) higher concentrations and viscosities.

