ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Application Of A Novel Temperature Shift Process For Particle Engineering

  Spray drying of amorphous dispersions improves solubility and bioavailability, enabling supersaturation in the intestine and driving higher absorption rates when compared to crystalline drug forms.

• Lyophilized Products Are On The Rise: What You Need To Know

  There is increased demand for lyophilization services in the manufacturing of new biologic drugs and injectable formulations as well as in change of formulation presentation.

• 3D Screen Printing: Enabling A New Generation Of Complex Formulations

  Screen-Printed Innovative Drug Technology can produce oral, transdermal, and implantable dosage forms while ensuring heterogeneous distribution of active ingredients.

• Selective Crystallization Of A Novel Polymorph

  Discover how applied rigorous characterization standards and expert knowledge of critical water activity enabled the isolation of a previously undiscovered and uncharacterized polymorph.

• A Robust Extractables Data Package Helps Drive Patient Safety

  Complex drug product formulations are more common, so it is imperative to have a deeper knowledge of extractables to understand risks associated with potential interactions between packaging and product.

• An Insoluble Problem? Oral Drug Solubility With Functional Polymers

  Review the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility and common questions on the topic.

• Oral Controlled Delivery Of Poorly Water-Soluble Drugs

  Various drug delivery nanotechnologies, such as nano-suspensions, lipid microemulsions, nano-emulsions, and amorphous solid dispersions, have been critical in overcoming bioavailability challenges.

• Precision Powder-In-Capsule Micro-Dosing Accelerates Drug Development

  Precision powder microdosing makes it possible to quickly get formulations to the clinic, saving time, money, and use of limited APIs.

• Reduce Costs And Improve Adherence For Self-Administration Of Biologics

  There is a growing trend toward wearable injectors for bolus delivery in order to help improve adherence and lower the costs of therapy. 

• Leachables Method Development, Validation And Relevant ICH References

  It is crucial to develop and validate analytical methods capable of detecting a wide range of potential organic and inorganic leachables specific to the drug and its packaging.