Emerging therapies are being designed to safely deliver oligonucleotides to disease-relevant tissues. Delivery is no longer a technical hurdle to overcome but a strategic lever.
- PLGA: A Workhorse Polymer Behind Modern Depot Long-Acting Injectables
- Designing Nanoparticles: Why Size Comes First
- Why Operational Readiness Is The Missing Piece In Biosimilar Adoption
- From Vial To Prefilled Syringe: Mastering The Development Transition
- Rethinking The Blueprint For Bone Regeneration: The Next Evolution In Orthobiologics
- Can We Cure Diabetes?
- Reassessing Nanoparticle Immunotoxicity: From Well-Established To Novel Approaches
- Delivery Device Functional Scrutiny: Can You Pass (Without) The Test?
ON-DEMAND WEBINARS
Process parameter and quality attribute relationships, including those for typical pre- and post-ASD unit operations, will be explored in the context of real-world examples.
The simultaneous spray drying of multiple ingredients is a powerful technique for making inhaled products with multiple actives. Examine how novel techniques can make these products a reality.
See how an amorphous solid dispersion (ASD) of acalabrutinib was designed using in vitro studies and in silico modeling. Understand how ASD formulations can enhance bioavailability.
Explore insights on extractables, focusing on how they relate to the revised EU GMP Annex 1, new and evolved expectations under USP <382>, and the use of VHP decontamination in aseptic environments.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![blood pressure test smartwatch, wearable medical devices-GettyImages-2211444948]( "Extending The Reach Of Critical Care: Remote Sensing")
Extending The Reach Of Critical Care: Remote SensingIn emergencies, scarce data delays decisions. Remote sensing — radar, thermal, and vision — assesses patients at a distance, enabling faster triage, smarter resource use, and more informed care.
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![GettyImages-1310024666-genetic-digital-dna]( "How Nanoparticle Platforms Are Unlocking Genetic Medicine's Potential")
How Nanoparticle Platforms Are Unlocking Genetic Medicine's PotentialExplore how the HIT SCAN platform accelerates gene therapy delivery by screening polymeric nanoparticles, enhancing precision and regulatory pathways for next-generation genetic medicines.
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![GettyImages-2161651129_elderly pharmacy]( "A Taste Masked And Easily Swallowed Malaria Drug For Elderly Patients")
A Taste Masked And Easily Swallowed Malaria Drug For Elderly PatientsDysphagia impacts treatment compliance and disproportionately affects the elderly. Learn how microencapsulation enabled formulation of a water-soluble powder drives patient adherence.
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![GettyImages-1284529278-syringe-pre-filled-PFS]( "Building Sustainability Into Medical Devices")
Building Sustainability Into Medical DevicesMedical device waste is a growing problem in the pharmaceutical industry. Learn how to navigate the balance between sustainability and factors like performance, safety, and regulatory compliance.
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![GettyImages-1293772957-scientist-laboratory-computer-drug-development]( "Solving For The Future Of Drug Delivery")
Solving For The Future Of Drug DeliveryNext-gen therapeutics require equally advanced delivery systems—localized, personalized, and precise—to ensure efficacy, safety, and scalability. Delivery is now a central driver of innovation.
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![Signing contract-GettyImages-1405364155]( "Contract Design And Development Vs. In-House: How To Find The Best Fit")
Contract Design And Development Vs. In-House: How To Find The Best FitExplore the rationale behind opting for a contract development organization (CDO) to fulfill organizational requirements and underscore vital considerations for evaluating CDOs to ensure alignment with your project objectives.
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![131]( "Gamification: The Answer To Pharma's Non-Adherence Crisis?")
Gamification: The Answer To Pharma's Non-Adherence Crisis?Digital connectivity is transforming the consumer experience and digital technology can now improve the patient experience too, in ways that were just not possible before.
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![GettyImages-1284529278-syringe-pre-filled-PFS]( "Sterile Injectable Therapies: Revolutionizing Lifecycle Management")
Sterile Injectable Therapies: Revolutionizing Lifecycle ManagementThe right balance of technical understanding, logistics, regulatory guidelines, and knowledge about product stability and quality is crucial for capitalizing on the benefits of shifting delivery formats.
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![iStock-1278412677-oncology-cancer-patient]( "Accelerating The Development Of Oncology Medicines")
Accelerating The Development Of Oncology MedicinesOncology drug development has seen a significant shift in focus, as molecule chemistries and drug technologies have improved. Explore five areas for consideration and the potential emerging solutions.
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![GettyImages-1365580848-ubiquinol-softgel]( "Seven Softgel Myths: Are You Missing Your Softgel Opportunity?")
Seven Softgel Myths: Are You Missing Your Softgel Opportunity?Softgels are a popular dose format among consumers, thanks to their high swallowability and quick onset of action, yet pharmaceutical developers may not even consider them. Why the disconnect?
TOM'S TAKES ON DRUG DELIVERY
TALKING WITH TOM VIDEOCASTS
Fran offers keen industry and technical insights exclusively on Drug Delivery Leader.
DELIVERED BY DEGRAZIO
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![Delivered _by _DeGrazio_Logo_Color_2]( "From Vial To Prefilled Syringe: Mastering The Development Transition")
From Vial To Prefilled Syringe: Mastering The Development TransitionIn this article, Fran DeGrazio discusses the opportunities, challenges, and benefits for biopharmaceutical product developers in transitioning from vial-based to prefilled syringe (PFS) delivery approaches. She lays out key differences and added complexities in areas such as device functionality, risk management, regulatory pathways, use of materials, lifecycle management, and organizational alignment.
FREE EBOOK
Why Human Factors Are Critical To Drug Delivery Device Success
In today’s highly competitive biopharma market, successful therapies prioritize the patient experience. Increasingly, patients expect to receive advanced therapies at home or in decentralized care settings, which require delivery methods that are easy to use and comfortable.
This collection explores how drug delivery teams can incorporate patient-centricity across development, from early human factors strategies to modality selection, ensuring safe, effective therapies that translate to real-world care.
