Building Confidence In Combination Product Development Through Pre-Verified Syringe-Device Configurations

By Chiara Carraro and Enrico Barichello

Based on an article that was originally published in ONdrugDelivery.

Developing self-administered injectable therapies introduces complex challenges, particularly when balancing formulation characteristics like high viscosity and concentration with reliable delivery performance. Selecting the right primary container and delivery device early in the process is essential to mitigating technical risks, avoiding unexpected injection times, and maintaining consistent functionality throughout shelf life. Utilizing pre-verified configurations helps pharmaceutical development teams make evidence-based decisions without starting from scratch. By generating robust compatibility data using representative test models rather than water, teams can better understand component interactions, ensure accurate dose delivery, and maintain stable injection times over real-time ageing. Accessing comprehensive insights and data packages streamlines the development journey and supports greater confidence ahead of commercial launch.

Read the full article to explore detailed findings from stability studies and learn how pre-verified configurations can de-risk your next combination product project.