Newsletter | June 2, 2025

06.02.25 -- Combination Platform Delivery In Immuno-Oncology

FEATURED EDITORIAL

Combination Platform Delivery In Immuno-Oncology

Fundamental goals of immuno-oncology therapies are to generate T-cell responses and overcome immunosuppression. In this episode of Sit and Deliver, host Tom von Gunden talks with Syncromune CEO Eamonn Hobbs about using injection- and infusion-based drug-device combination therapies in targeting solid tumor cancers.

Design Controls For Delivery Devices, Part 2: Practical Tips

Here, the author provides recommendations for implementing Design Controls in the development of combination products and other drug delivery devices. In outlining tips for drug-device product developers, DeGrazio focuses on key considerations, including risk management, chemical and functional compatibility, and regulatory compliance.

INDUSTRY INSIGHTS

3D Screen Printing For Delivering Complex Formulations

Screen-Printed Innovative Drug Technology can produce oral, transdermal, and implantable dosage forms while ensuring heterogeneous distribution of active ingredients.

Elastomer Formulations And Vial Containment Performance

Examine the results of two, two-year studies that indicate good container closure integrity performance that can be achieved with stoppers of a given elastomer, independent of configuration.

Key Considerations For Dry Powder Inhalation Delivery

A focus on spray-drying expertise in pulmonary and nasal powder development highlights why it is vital to choose the right CDMO.

Nanoparticle Formulations For Patient-Centric Dosing

Explore how bioavailability of poorly soluble APIs can be improved and patient compliance enhanced by reducing the size or number of tablets that a patient must take to achieve the required dose.

Gliding Towards De-Risked Combination Product Development

Learn about the critical role plunger stoppers play in determining a combination drug product's exposure to extractables and leachables.

SOLUTIONS

Fill-Finish Capacity Update: Inside A $200M Expansion