06.06.26 -- Drug Delivery Leader Best Of May

IV → SC is a system design challenge. Success depends on aligning formulation, device, manufacturing, and clinical strategy early to avoid costly failures and redesigns.

In this segment of the Drug Delivery Leader Live online event, Large Molecule Biologics Delivery: Aligning Formulations, Doses, And Devices, Chief Editor Tom von Gunden directs to panelist Dominick DeGrazio an audience question about wearable devices versus autoinjectors for frequent dosing of biologics. DeGrazio describes key factors in the decision including dose volume, injection rate, and patient preference and compliance. 

Courtney Nicholas Sutton, Head of Product Strategy at drug delivery systems developer and manufacturer SHL Medical, joins Supplier Horizons host Tom von Gunden to discuss opportunities for multidose pen injection technologies to advance patient adherence and therapeutic benefits. With the primary treatment scenario being chronic, cardiometabolic diseases, the discussion covers topics including dosing accuracy, human factors, and device reusability. 

A novel valve provides dual‑chamber functionality within standard syringes, keeping two liquid drugs separated until injection while reducing development risk through advanced modeling.

Review the regulatory classification of LNPs, liposomes, and novel excipients, as well as specific requirements outlined in regulatory guidance documents and strategies to navigate challenges.

Developing new delivery routes is essential for creating more effective treatments. Nanoforming enables new routes to simplify dosing, enhance patient comfort, and reduce healthcare costs.