How To Address Challenges In Oncology Drug Containment

By T. Page McAndrew

Drug product containment systems comprising Daikyo Crystal Zenith® cyclic olefin polymer (COP) vials have advantages over those comprising glass vials. When matched with NovaPure® stoppers, container closure integrity (CCI) performance has been quantified for oxygen and carbon dioxide, at temperatures from room temperature through cryogenic temperatures, with excellent system performance. For these reasons, they are an excellent choice for oncology therapies, in particular those based on gene and cell therapies that require cryogenic storage.