11.18.24 -- Intranasal Delivery For Post-Viral Smell Loss With Cyrano Therapeutics

Using off-the-shelf (OTS) devices can significantly benefit development programs. When utilizing OTS devices, understand the sponsor's design control responsibilities.

Explore how the widespread adoption of autoinjectors is transforming the biopharmaceutical industry's approach to drug delivery, offering precise dosing, patient adherence, and safety.

Review the pros and cons of marketed amorphous solid dispersions with new, unpublished data, and explore a green alternative: advanced nanotechnology for nanocrystal manufacturing.

Specific dosing guidelines and acceptable dosage forms for pediatric patients need to be developed to optimize therapeutic efficacy and limit and prevent serious adverse side effects.

How to approach the transition of migrating from a vial to a syringe or cartridge, the necessary compatibility testing, and the stresses on the bulk product during formulation and filling.

Physiologically based pharmacokinetic modeling is a powerful tool for clinical trial design that can be leveraged alongside early development experiments to reduce costs and accelerate timelines.