Newsletter | July 14, 2025

07.14.25 -- Long-Acting Implants For Treating Chronic Conditions

FEATURED EDITORIAL

Long-Acting Implants For Treating Chronic Conditions

The popular GLP-1 agonists employed in treating obesity and Type 2 diabetes are commonly administered via weekly injections. Videocast host Tom von Gunden talks with CEO Adam Mendelsohn of Vivani Medical about enhancing patient adherence via long-acting, controlled release implants.

Oral Solid Dosage Formulation And Development: A Case Study

This case study involves a drug substance currently in the preclinical phase. Discussion includes API physical chemical characteristics, enabling technologies, formulation assessment, and more.

INDUSTRY INSIGHTS

PBPK Modeling For Optimizing Controlled Release Dosage Forms

Explore the benefits of controlled release, PBPK modeling’s role in formulation, and how modified release products optimize patient outcomes.

Spray Drying To Enable New Inhaled Drug Products

The formulation and spray drying process can help manufacture a stable, highly respirable powder and deliver products that require a high drug load, a biologic, or rapid onset therapeutic.

Computational Modeling Of Injection-Related Tissue Responses

Optimizing delivery along with the formulation is the key to successful clinical outcomes. Research is necessary to understand the relationship between body morphology, injection force, and needle length.

Subcutaneous mAb Delivery Using Nanoformed Particles

A highly concentrated non-aqueous suspension of an IgG1 was developed using a patented platform. Review how the particle size of the monoclonal antibody (mAb) impacts the behavior of the drug product.

Solving The Silicone Challenge In Pre-Fillable Syringes

Discover a technology platform that is revolutionizing the pre-fillable syringe market by solving the challenge of silicone sensitivity, ensuring stability for sensitive drugs.

Wearable Injectors: An Alternative To Intravenous Administration

See a quick visual summary of findings from an early feasibility clinical study featuring a 2-5 mL wearable injector with a viscous placebo.

SPONSOR

Join the PDA Universe of Pre-Filled Syringes and Injection Devices Conference 2025, taking place 21–22 October in Vienna, Austria! Centered on the theme Shaping the Drug Delivery Ecosystem, this event explores innovation at the intersection of science, technology, sustainability, and patient experience. Expect powerful keynotes, real-world case studies, expert sessions, and a dynamic exhibition showcasing the future of injectable combination products. Make sure to register!

SOLUTIONS

Selecting A CDMO: A Guide To Successful Collaboration

Streamlining Design Assessment For Generic Combination Products

Daikyo Crystal Zenith Ready-To-Use Nested Vials