NanoImprove The Performance Of Your Biologic Formulations: Higher Drug Loads For Subcutaneous And Inhaled Delivery Of Novel And BioBetter Products

Nanoform’s proprietary nanotechnology solutions, supported by their Biotechnology Platform, are designed to improve the performance of biologic formulations, including peptides and proteins, by producing superior quality solid nano- or micron-sized particles. This approach, called Nanoforming, enables improved routes of administration and higher drug loads.

A key benefit of Nanoforming is the ability to create perfect, spherical particles that lead to high-concentration suspensions with low injection forces, making them suitable for subcutaneous delivery with drug loads as high as 500 mg/ml. Furthermore, the resulting dry powder APIs offer improved long-term stability and are highly flowable and aerodynamic for inhalation delivery, achieving a high Fine Particle Fraction (FPF) for deep-lung deposition. Case studies demonstrate the technology's success in simplifying high-concentration subcutaneous trastuzumab formulations and creating an optimal dry powder Semaglutide inhaler formulation.