Non-Viral Gene Delivery (NVGD) Using Polymeric-Nano Particles

Battelle's Non-Viral Gene Delivery (NVGD) platform tackles the primary obstacle hindering gene editing therapies: efficient delivery. Utilizing engineered nanoparticles with significantly expanded payload capacity (exceeding ten times the five-kilobase limit of viral vectors), the platform overcomes limitations associated with payload size. Notably, NVGD combines a high-throughput synthesis platform with in vivo tracking and machine learning-driven design.

This synergistic approach allows for parallel in vitro and in vivo screening of a vast library of nanoparticles, accelerating the identification of optimal delivery vehicles for diverse therapeutic applications. By addressing the payload challenge and facilitating streamlined candidate selection, NVGD holds significant promise for advancing the field of gene editing therapy.

Battelle Drug Delivery | Battelle Solution