Overcoming Formulation Challenges For mRNA Or High-Concentration Proteins
![LIQUID CHROMATOGRAPHY-MASS SPECTROMETER GettyImages-1205683338 LIQUID CHROMATOGRAPHY-MASS SPECTROMETER GettyImages-1205683338](https://vertassets.blob.core.windows.net/image/23c67c84/23c67c84-1541-4133-a32e-59517337cf42/375_250-liquid_chromatography_mass_spectrometer_gettyimages_1205683338.jpg)
In recent years, the industry witnessed new demand for protein delivery and the emergence of advanced modalities, such as mRNA. However, their development is met with technical challenges, including high-concentration formulations, stability and degradation. To address those concerns, optimizing formulation components, including high-throughput analytics methods, automation, statistical approach, and excipient design can help. In this webinar, experts will discuss how to improve the formulation development of high-concentration mAbs for subcutaneous delivery to reduce viscosity, and potentially reduce costs and timelines, and how to overcome current challenges met in formulating mRNA lipid nanoparticles (mRNA-LNP).
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