Small Is Powerful And Sustained

Formulating biologics for a subcutaneous administration route instead of an intravenous one may allow a lower number of injections, or even substitute the need for long-time infusions administered at a hospital. The latter can necessitate frequent and costly hospital trips which can have a cascading effect on compliance as patients struggle to keep appointments and follow treatment courses.

Sustained-release parenteral formulations or implants that allow local administration of the drug are key to solving the major issues faced by patients prescribed injectable therapeutics. They can reduce the expense and time commitment for patients, improving compliance and positively impacting quality of life. Sustained-release implants can also enable improved local drug delivery efficiency by concentrating the drug at the target site, thereby minimizing systemic exposure and resultant adverse side effects.

In this article, explore opportunities to enhance sustained-release implants.