Webinar

Solid Form Screening Of Active Pharmaceutical Ingredients

Source: Lonza
GettyImages-1346675538-lab-research-development-test tubes

Solid form services is the bridge between drug substance and drug product development for New Chemical Entities (NCEs). Early screening, selection, and isolation of the lead polymorph can avoid additional costs and delayed timelines due to the unexpected appearance of stable polymorphs late in development. Solid form screening of salts and cocrystals, on the other hand, can provide a stable crystalline form capable of solubility enhancement for poorly soluble drugs to improve bioavailability.

In this webinar, we discuss the role of solid form services in helping meet the accelerated timelines of the drug development lifecycle. Also, we share examples of robust workflows for fast and thorough solid form screens. A case study reviews the polymorph screen of a late stage API focusing on monotropic vs enantiotropic polymorphs. We also highlight the crystallization process development of the lead form.

Key Learning Objectives:

  • Importance of solid form screening and form selection in pharmaceutical development
  • Understand how monotropic and enantiotropic polymorphs are screened
  • Appreciate design considerations for robust crystallization processes for lead forms
access the Webinar!

Get unlimited access to:

Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Drug Delivery Leader? Subscribe today.

Subscribe to Drug Delivery Leader X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.

or

Subscribe to Drug Delivery Leader