Newsletter | September 23, 2025

09.23.25 -- Unlocking Nanomedicine, Patient-Centered Delivery, And Scaling Genetic Therapies

Unlocking New Possibilities For Treating Rare Genetic Diseases

With over 7,000 rare diseases, most of which are genetically linked, the potential for nanomedicine to revolutionize treatment is immense. While polymer nanoparticles offer unique advantages, like the ability to engineer specific attributes, several challenges remain.

 

The Paradigm Shift: From Scale-Up To Scale-Out In Genetic Medicine

When applied to the manufacturing of emerging genetic medicines, the “scale-out” approach is poised to revolutionize production by enhancing speed, safety, and regulatory efficiency while reducing costs and expanding patient access to critical treatments.

 

The Road To Agile Pharmaceutical Manufacturing

As demand grows for faster development timelines and more resilient supply chains, manufacturers must embrace a more agile approach. Battelle helped a specialty pharma company pioneer in-package 3D printing to manufacture customized tablets directly into blister packaging.

 

Is The Autoinjector Dead? The Future Of Patient-Centered Drug Delivery

Autoinjectors have transformed how we deliver—and think about—injectable drugs, but advances in drug formulation, alternative delivery platforms, environmental considerations, and patient expectations are all reshaping the landscape and raising new questions.

 

Microphysiological Systems: Closing The Gap Between Models And Medicine

Microphysiological systems (MPS) have generated tremendous excitement over the past decade as a more human-relevant alternative to animal models. The question now: how far can they go in transforming drug discovery, safety testing and, ultimately, patient care?