Featured Products & Services

1. Blow/Fill/Seal Packaging Systems 7/9/2020

   Weiler Engineering’s ASEP-TECH^® Blow/Fill/Seal machines are ideal for processing temperature sensitive products such as biological and protein-based materials – providing a level of enhanced sterility assurance.

2. A User-Friendly Solution For Fill-Finish Professionals 1/31/2024

   When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.

   Does an isolator need to be ergonomically unfriendly to clean?

   Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).

   Does routine maintenance have to be time-consuming and laborious?

   Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?

3. Pharmaceutical Vial Filling Equipment: VFM 4/28/2021

   VFM automatic filling and stoppering machines are designed for injectable solutions in vials.

4. Pharmaceutical Filling System For Non-Injectable Products: Ophthalmic, Nasal Sprays, Syrups: OFM 4/27/2021

   OFM automatic filling and closing machines are designed for pharmaceutical formulations, such as syrups, ophthalmic products, and nasal sprays either in glass or plastic containers.

5. Nasal Dosage Form Development 10/23/2024

   Upperton have developed UpperNose™, a nasal product development approach designed to streamline the development process for nasal dosage forms.

6. Robotic Multi-Format Filling & Closing System 1/2/2020

   AST’s ASEPTiCell® is a flexible fill/finish system that can efficiently process medium-sized clinical and commercial batches while meeting all cGMP requirements for cleanliness and sterility.

7. A Breakthrough Solution For Biologics 8/25/2023

   Medicines are highly sensitive to primary packaging components, which can affect compatibility with container closure systems. Discover Alba® syringes, designed for sensitive biologics, including highly concentrated drugs vulnerable to silicone interaction and ophthalmic medications.

8. Pharmaceutical De-Nesting Equipment For Syringes And Cartridges 4/22/2022

   The DNS machines are designed for de-nesting pharmaceutical syringes and cartridges in nest without damaging them. Thanks to their precision, you can reach a higher speed and automatically connect the filling machine with the final production system. DNS machines are characterized by: Robotized precise handling of pharmaceutical syringes/cartridges, Automated tub and nest handling, Convenient operation with touch screen, and Secure and efficient recipe management.

9. Pharmaceutical Aseptic Filling Equipment 6/29/2022

   AST’s ASEPTiCell® and GENiSYS® systems combine industry-proven technologies such as robotics and isolator-barrier systems to provide flexible pharmaceutical aseptic filling and closing of ready-to-use vials, syringes, and cartridges with a single machine. These innovative platforms use a modular design approach to provide a truly adaptive system with the capabilities and features necessary for cGMP production of clinical and commercial sterile injectable products.

10. Automated Vision Inspection Systems For Injectable Drug Products: Vials, Syringes, Cartridges, Bottles 2/2/2022

    We offer a comprehensive range of automatic inspection machines for injectable pharmaceutical products contained in ampoules, vials, cartridges, syringes and bottles. Designed and manufactured to meet the most demanding technical requirements, our solutions feature different production speeds and advanced vision standards for an optimum performance.