Newsletter | August 12, 2024

08.12.24 -- Balancing Sustainability With Patient Safety In Medical Device Design

SPONSOR

Enhancing The Solubility Of High Lipophilicity Drugs Via Spray Drying

An R&D project has shown that the solubility and dissolution characteristics for Itraconazole can be improved by helping them to maintain an amorphous state after spray drying with selected hydrophillic polymers. This technique can be a useful tool for solubility enhancement when dealing with drugs with low solubility in BCS Class II and IV.

FEATURED EDITORIAL

Balancing Sustainability With Patient Safety In Medical Device Design

There is increasing pressure on manufacturers to make devices that combine safety and effectiveness with sustainability, particularly with regard to EU regulations and directives.

INDUSTRY INSIGHTS

The Importance Of Understanding Materials In Medical Product Development

Explore considerations for the series of characterizations necessary to ensure the efficacy of a packaging or device component and final drug delivery system.

Overcoming Formulation Challenges For mRNA, High-Concentration Proteins

Increased demand for protein delivery and the emergence of advanced modalities – including mRNA – are introducing new challenges to the development lifecycle, such as high-concentration formulations.

An Easy-To-Swallow Depression Drug For Elderly Patients

Examine how an innovative formulation approach helped a developer create a version of their drug that promotes treatment compliance within the geriatric population.

Strategies To Mitigate Common Pitfalls In Early Drug Development

Two experts discuss the ways companies can address issues with low bioavailability and the benefits of enlisting an experienced drug development partner.

A New Mindset For Combination Product Development

As we balance the time-to-market and risk for novel therapies, we must anticipate changing needs for combination device development, highlighting the technological paradigm shift.

Stainless Steel Needles: Quantifying Cobalt Risk For EU Regulation

Learn how a partner who is committed to ensuring the safety of medical devices by mitigating the risk of chemical interaction with drugs is crucial for navigating the regulatory pathway to approval.

SOLUTIONS

Navigating PFAS In Drug Delivery Devices

Real World Dosing Solutions For Patients

KinetiSol Amorphic Dispersions

Drug Product Manufacturing: Aseptic Fill Finish