Newsletter | September 30, 2024

09.30.24 -- LNP-Delivered mRNA Via Inhalation With Ethris' Carsten Rudolph And Thomas Langenickel

FEATURED EDITORIAL

LNP-Delivered mRNA Via Inhalation With Ethris' Carsten Rudolph And Thomas Langenickel

How can genetic information be carried into lung tissue for the treatment of asthma and potentially other conditions? In this inaugural episode of In Combination, host Tom von Gunden combines the perspectives of two executives from LNP/mRNA (lipidoid nanoparticle / messenger RNA) formulation and delivery platform developer Ethris: CEO Carsten Rudolph and Chief Medical Officer Thomas Langenickel. The conversation illuminates the value to patients of platform approaches to inhalation-delivered treatments.

INDUSTRY INSIGHTS

Characterizing Injection Factors And Their Impact On System Function

The transition of intravenous in-clinic chronic disease therapies to large volume subcutaneous injections in alternate settings has created an evolving roster of new formulations and treatment options.

Aligning Your Drug Delivery Device With Human Factors: Best Practices

Discover how patient-centric design principles can improve the development of medical devices. By focusing on user needs and behaviors, manufacturers can ensure that products align with expectations.

Nanoformed API: A Superior Alternative To Solid Dispersions

Nanotechnology is emerging as an alternative to ASD, able to not only address bioavailability challenges but also deliver higher drug loads in much more patient-friendly formats.

Achieving Patient Centricity, Commercial Viability In Pediatric Products

Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.

Improving Safety And Efficacy With Charged Variant Characterization

Discover how a CDMO with extensive experience in protein variant characterization, CQA analytics, and patient-centric product development can ensure the safety and efficacy of your biotherapeutic.

Identify And Mitigate Absorption Risks With PBPK Modeling

See how PBPK models combined with custom and off-the-shelf in vitro tools and solubility enhancement expertise can reduce the need for drug product reformulation or repeated preclinical or clinical studies.

SOLUTIONS

Nasal Spray Development And Manufacturing Services

Combination Products

Drug Product Fill Finish And Formulation Solutions