Articles, App Notes, Case Studies, & White Papers

  1. Platform Reduces Product Development Time And Cost By 30% 3/4/2022

    Using innovative capsule-filling equipment and processing technology, and mini-tablet and drug-layered beadlet manufacturing, you can have an adaptable, easily modified formulation.

  2. Overcoming Limitations To Achieve Uniform Dosing 1/24/2022

    An immediate need for lower dose capsules in the clinic posed several challenges in blend formulation with very tight timelines for delivery.

  3. Vial Containment Systems For Gene And Cell Therapies 5/24/2024

    CZ vial-stopper-seal combinations offer a viable solution for the challenges associated with low-temperature storage of cell therapy drug products.

  4. Delivering Market Success For Pharma Partners From Concept To Patient

    The development of drug delivery devices that are innovative, intuitive, patient friendly, and patient safe must address certain areas of concern that are particular to both biologic and biosimilar therapies.

  5. Solid Form Strategies For Increasing Oral Bioavailability

    Optimizing a drug’s solid form can improve its solubility and bioavailability when further molecular modifications are prohibitive.

  6. Age-Appropriate Pediatric Formulation Development 1/27/2022

    There is a significant variability in the pharmacokinetics of the same drug and dosage form between pediatric and adult populations, and the factors impacting drug bioavailability are different in children.

  7. A Smart, Data-Driven Approach To Formulate Biotherapeutics For PFS 3/5/2024

    Explore a unique model to predict injection force designed to decorrelate factors linked to formulation development and the ones linked to container and delivery device selection.

  8. New Polymer Overcomes Limits In Sustained Drug Delivery In Ophthalmology 3/29/2023

    Challenges specific to eye physiology complicate the development of new therapies and necessitate innovative drug delivery methods. Biodegradable polymers show promise in addressing these challenges.

  9. Delivering On GLP-1 Demand: Combining Device And Supply Strategy 5/7/2024

    Meeting the demand for GLP-1 treatments requires robust and efficient delivery systems. Review how innovative solutions offer customization, streamlined manufacturing, and formulation compatibility.

  10. Design And Packaging Advantages For Cell And Gene Therapy Drugs 9/3/2024

    With the increasing demand for cell and gene therapies, Crystal Zenith nested vials can help the biopharma industry overcome the challenges of scaling up manufacturing and logistics.