Oral Drug Delivery Articles

1. The Resurgence Of Fervor For Oral Delivery 10/7/2026

   In this article, Chief Editor Tom von Gunden reports on the science and technology boosting the rise in attention to oral methods for advanced drug and biologics delivery. The insights he illuminates include innovative approaches to increasing permeability, solubility, and bioavailability, as well as expanding the types and sizes of therapeutic payloads formulated for oral administration.

2. Rethinking Drug Delivery To Combat Antibiotic Resistance 10/7/2026

   Combating antibiotic resistance requires delivering therapeutic agents to the right pathogen, cellular target, and site of infection while limiting unnecessary exposure elsewhere.

3. FDA Modernizes Container Closure Guidance: What Is Changing And Why It Matters 10/1/2026

   The proposed revision reflects changes in packaging technology, drug delivery systems, quality risk management, and more that have occurred since 1999's guidance.

4. Engineering Medical Devices To Improve Oral Delivery Of Biopharmaceuticals 9/10/2026

   Two approved GLP-1 pills validated the demand — and exposed the ceiling that only delivery devices can break.

5. Oral Combination Therapies: Navigating Development Complexities 9/10/2026

   We discuss how delivery strategy influences development decisions, learnings from advancing IHL-42X, and Latham's perspective on the future of patient-centric drug delivery.

6. Need A Drug Delivery Conversation Starter? Try Target Product Profile 5/18/2026

   In this article, Chief Editor Tom von Gunden explores the need for and existence of cross-functional communication during drug product development and delivery device selection. He consults industry veterans with experience in various formulation or delivery roles at GSK and Merck. They identify the Target Product Profile (TPP) as the core concept guiding collaboration. 

7. Treatment Adherence And Designing Therapeutics To Meet Patient Needs 5/6/2026

   Reformulation improves adherence by reducing pill burden and side effects, enhancing real-world usability and align therapies with diverse patient needs.

8. Gaining An Edge In GLP-1 Production 5/5/2026

   The shortage-driven production of GLP-1 drugs of the past few years is giving way to a long-term operation model characterized by digital enablement and supply chain resilience.

9. Patient-Centric Drug Delivery: Do Possible And Preferable Always Align? 4/22/2026

   In this article, Chief Editor Tom von Gunden discusses the alignment of drug delivery method with patient preference and need. He reflects on recent conversations in which he heard from experts in drug and delivery product development, as well as patients themselves, about patient-centric considerations such as safety, efficacy, usability, and convenience. The primary use case is the transition from clinically administered IV to subcutaneous injection, including self-administration.

10. Beyond Biologics: A Biophysical Approach To Crohn's Disease 4/2/2026

    Research into a nano-amorphous approach suggests a new breakthrough in Crohn’s management may come from a shift toward modulating the biophysical environment of the gut.