Inhalation Drug Delivery Resources

1. Complex Molecules, Complex Problems

   The support of an experienced CDMO is critical to overcoming complexity when working with highly potent APIs and when solving solubility challenges.

2. Contract Design And Development Vs. In-House: How To Find The Best Fit 3/21/2024

   Explore the rationale behind opting for a contract development organization (CDO) to fulfill organizational requirements and underscore vital considerations for evaluating CDOs to ensure alignment with your project objectives.

3. Streamlining The Path To Market For Generic Drug-Device Combinations 9/18/2024

   Developing g-DDCPs is a complex and time-consuming process. By using a risk-based approach, manufacturers can streamline the development process and bring g-DDCPs to market more quickly.

4. Examining The Emergence Of Unit- And Bi-Dose Nasal Sprays 2/8/2022

   Nasal spray administration of medicine offers advantages over oral and IV delivery. Experts discuss the advantages and opportunities of adopting unit- and bi-dose nasal delivery technology.

5. Formulation Development From Preclinical To First-In-Human 1/24/2022

   A compound with poor biopharmaceutical properties or improper formulation design could lead to a delay in the project or even program termination.

6. 10 Ways To Align Your Medical Device With Human Factors Industry Best Practices 3/1/2024

   Discover how patient-centric design principles can improve the development of medical devices. By focusing on user needs and behaviors, manufacturers can ensure that products align with expectations.

7. Improving Toxicology Testing For Inhalation Products 1/22/2024

   By embracing new approach methods, regulatory agencies can revolutionize toxicology testing. These methods can be adapted for various medications, including inhalers and nasal-administered drugs.

8. Simultaneous Spray Drying For Combination Dry Powder Inhaler Formulations 7/12/2022

   Three combination case studies are demonstrated, in which bevacizumab is paired with erlotinib, cisplatin, or paclitaxel in a dry powder inhaler formulation.

9. Engineering Approaches To Respiratory Drug Delivery 5/27/2022

   Explore the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.

10. Understanding The In-Vitro/In-Vivo Relationship (IVIVR): Inhaled Medicinal Products 11/8/2021

    IVIVR modeling leverages in-vitro testing knowledge toward predicting in-vivo testing results, often reducing long-term development costs by facilitating more informed decision-making during drug development.