Inhalation Drug Delivery Resources

  1. Simultaneous Spray Drying For Combination Dry Powder Inhaler Formulations 7/12/2022

    Three combination case studies are demonstrated, in which bevacizumab is paired with erlotinib, cisplatin, or paclitaxel in a dry powder inhaler formulation.

  2. Understanding The In-Vitro/In-Vivo Relationship (IVIVR): Inhaled Medicinal Products 11/8/2021

    IVIVR modeling leverages in-vitro testing knowledge toward predicting in-vivo testing results, often reducing long-term development costs by facilitating more informed decision-making during drug development.

  3. Precision Powder-In-Capsule Micro-Dosing Accelerates Drug Development 6/1/2022

    Precision powder microdosing makes it possible to quickly get formulations to the clinic, saving time, money, and use of limited APIs.

  4. Streamlining The Path To Market For Generic Drug-Device Combinations 9/18/2024

    Developing g-DDCPs is a complex and time-consuming process. By using a risk-based approach, manufacturers can streamline the development process and bring g-DDCPs to market more quickly.

  5. Combination Products: Market Trends And Regulatory Considerations 1/17/2024

    Combination products provide significant avenues for increasing patient adherence and overall efficacy. This collection outlines the opportunity and identifies strategies for gaining regulatory approval.

  6. Formulation Development From Preclinical To First-In-Human 1/24/2022

    A compound with poor biopharmaceutical properties or improper formulation design could lead to a delay in the project or even program termination.

  7. Using 505(B)(2) To Streamline Approval Of Combination Products 2/2/2023

    In recent years, the quantity of approvals for products and 505(b)(2) applications has risen, causing developers to map out their regulatory strategy as early as possible.

  8. Simultaneous Spray Drying For Large/Small Mol Combinations 8/9/2022

    Gain insights into a “simul-spray” process pioneering for combining small and large molecules into a single, atomized drug product for inhalation administration.

  9. Engineering Approaches To Respiratory Drug Delivery 5/27/2022

    Explore the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.

  10. The Gateway Delivery To The Brain 1/30/2026

    Nose‑to‑brain delivery enables targeted neurological treatment by using direct neural pathways to boost precision and limit systemic exposure, with new formulations and devices driving rapid progress.