Inhalation Drug Delivery Resources

1. Intranasal Drug Product Development—From Formulation To Scale-Up Manufacturing 3/8/2024

   Explore the key advantages of intranasal drug delivery, including its potential to rapidly treat conditions like migraines and headaches, and deliver medications directly to the brain.

2. Simultaneous Spray Drying For Combination Dry Powder Inhaler Formulations 7/12/2022

   Three combination case studies are demonstrated, in which bevacizumab is paired with erlotinib, cisplatin, or paclitaxel in a dry powder inhaler formulation.

3. Streamlining The Path To Market For Generic Drug-Device Combinations 9/18/2024

   Developing g-DDCPs is a complex and time-consuming process. By using a risk-based approach, manufacturers can streamline the development process and bring g-DDCPs to market more quickly.

4. Application Of A Novel Temperature Shift Process For Particle Engineering

   Spray drying of amorphous dispersions improves solubility and bioavailability, enabling supersaturation in the intestine and driving higher absorption rates when compared to crystalline drug forms.

5. Six Inhaler Sustainability Myths – And Why They Must Be Busted 3/9/2022

   The solution to the carbon footprint of respiratory disease is complicated. The prevailing “myths” must be examined and addressed to achieve the shared industry vision of a decarbonized inhaler market.

6. Spray Drying To Enable New Inhaled Drug Products 7/11/2023

   The formulation and spray drying process can help manufacture a stable, highly respirable powder and deliver products that require a high drug load, a biologic, or rapid onset therapeutic.

7. Solutions For Accelerated Pharmaceutical Development

   Explore an integrated service package designed to simplify and accelerate the development pathway, even for APIs with challenging properties such as low aqueous solubility and poor bioavailability.

8. New Technologies To Improve Solubility Of Brick Dust Compounds 7/13/2022

   David Lyon, Ph.D., and Molly Adam answer attendee questions from a recent webinar about three enabling technologies designed to improve drug solubility in organic solvents for spray drying.

9. 10 Ways To Align Your Medical Device With Human Factors Industry Best Practices 3/1/2024

   Discover how patient-centric design principles can improve the development of medical devices. By focusing on user needs and behaviors, manufacturers can ensure that products align with expectations.

10. Application Of Nano-Emulsion Technology To Address Unmet Medical Needs: A Case Study Of Clopidogrel IV By 505(b)(2) Pathway 1/26/2022

    Review a process where the insoluble and unstable free-base form of clopidogrel is converted to a form with acceptable drug loading and is protected from chemical degradation.