Injectable Drug Delivery Articles

1. Designing For Precision: How Delivery Is Shaping Cancer Treatment 10/19/2026

   Precision oncology has transformed who receives treatment and what biology we target. The next frontier is designing where therapeutic activity occurs.

2. Antibody–Oligonucleotide Conjugates, Part 2: Manufacturing 10/16/2026

   Let's delve into manufacturing strategy, conjugation chemistry, process development and scale-up, and purification: the central manufacturing challenge.

3. Intratumoral Treatment Of Cancer: After Many Prior Attempts, Has The Time Finally Come? 10/15/2026

   Several companies are in Phase 3 development of intratumoral drug products, all with a lead product in a cancer other than melanoma, based on novel chemistry.

4. Antibody–Oligonucleotide Conjugates, Part 1: Approaching Your AOC Development Plan 10/9/2026

   The emergence of antibody–oligonucleotide conjugates (AOCs) addresses delivery issues with huge potential. Let's look at how to approach your development plan with molecular architecture, defining the target product profile, and CQAs.

5. Drug–Device Combination Products: Bridging Formulation, Device, And Manufacturing Decisions 10/8/2026

   Teams must assess the drug, the device, the manufacturing process, and the environment in which the product is used as an integrated system, not as separate parts. 

6. Rethinking Drug Delivery To Combat Antibiotic Resistance 10/7/2026

   Combating antibiotic resistance requires delivering therapeutic agents to the right pathogen, cellular target, and site of infection while limiting unnecessary exposure elsewhere.

7. Advancing Multi-Pathology Disease-Modifying Therapy For Neurodegenerative Diseases 10/6/2026

   We discuss Amyl’s approach to developing therapeutics designed to target multiple amyloid fibrils and the use of brain shuttle technology to enhance delivery across the blood-brain barrier.

8. Qualification And Validation Of Depyrogenation Tunnels And Autoclaves 10/2/2026

   Systemic vulnerabilities exist in thermal uniformity assurance, steam penetration verification, regulatory fragmentation, and tech harmonization. 

9. FDA Modernizes Container Closure Guidance: What Is Changing And Why It Matters 10/1/2026

   The proposed revision reflects changes in packaging technology, drug delivery systems, quality risk management, and more that have occurred since 1999's guidance.

10. What Patients Actually Want From Connected Drug Delivery 9/29/2026

    A recent survey conducted with BioPhorum members revealed that the most critical aspect of digital healthcare for drug delivery devices. Let's take a closer look.