Ocular Drug Delivery Solutions

  1. Aseptic Filling Systems For Biopharmaceutical Manufacturing 3/28/2023

    AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.

  2. Controlled Expansion Of Supercritical Solutions (CESS®) Technology 4/24/2023

    Nanoform’s award-winning Controlled Expansion of Supercritical Solutions (CESS®) technology is a bottom-up nanoparticle engineering approach that enables the creation of API nanoparticles and can unlock the full therapeutic potential of small molecule drugs.

  3. Bionanoparticle Technology 4/24/2023

    Nanoform’s proprietary bionanoparticle technology can deliver large-molecule drug particles as small as 50 nm while retaining biological activity. This can not only enable more patient-friendly approaches to drug delivery, but also potentially higher loads of active ingredients.

  4. Pharmaceutical Vial Filling Machine With Isolator 5/3/2023

    Rotary filler for clinical and early-stage pharma production specialized for fill finish advanced aseptic manufacturing for pharmaceutical and biologics injectables. Designed to be used in an isolator.

  5. Fill Finish Solution - Maximize Drug Product Recovery 7/12/2023

    Analyze a family of fill/finish solutions that offers a complete, configurable solution for biopharmas and CDMOs looking to maximize drug product recovery.

  6. A Breakthrough Solution For Biologics 8/25/2023

    Medicines are highly sensitive to primary packaging components, which can affect compatibility with container closure systems. Discover Alba® syringes, designed for sensitive biologics, including highly concentrated drugs vulnerable to silicone interaction and ophthalmic medications.

  7. A User-Friendly Solution For Fill-Finish Professionals 1/31/2024

    When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.

    Does an isolator need to be ergonomically unfriendly to clean?

    Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).

    Does routine maintenance have to be time-consuming and laborious?

    Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?

  8. Proven Vial Containment That Scales From R&D To Commercial 2/20/2024

    Speed up your time to market and reduce your risk of selecting individual components that may not work well together by choosing the Ready Pack containment solution.

  9. Injecting Sustainability Into Medical Device Design 3/1/2024

    Learn how the right sustainable approach to medical device design is crucial in addressing the sustainability challenge in the industry.

  10. Transforming Drug Delivery 3/1/2024

    Learn how our team of scientists, engineers, and human-centered designers, as well as our world-class facilities, empower us to confidently guide your product toward a successful market launch.