Ocular Drug Delivery Solutions

  1. Pharmaceutical Aseptic Filling Equipment 6/29/2022

    AST’s ASEPTiCell® and GENiSYS® systems combine industry-proven technologies such as robotics and isolator-barrier systems to provide flexible pharmaceutical aseptic filling and closing of ready-to-use vials, syringes, and cartridges with a single machine. These innovative platforms use a modular design approach to provide a truly adaptive system with the capabilities and features necessary for cGMP production of clinical and commercial sterile injectable products.

  2. Sterile Formulation Development 7/1/2022

    With over 20 years of experience, PCI’s strength lies in our ability to manage products with unique challenges ranging from small molecules presenting with solubility issues or a labile molecule that is only stable as a liquid presentation for a short time.

  3. Modified-Release Formulation Strategies 7/26/2022

    Learn what oral modified-release (MR) dosage forms can offer and why they continue to rise in popularity.

  4. Drug Product Services: Pre-Formulation To Commercial-Scale Production 8/17/2022

    Our experts support clients with pre-formulation, formulation, process and analytical development, as well as production and registration. We’ve worked on a range of both oral solid dosage and injectable projects for clients over the years.

  5. Biodegradable Polyester Amide Platform For Sustained Delivery Solutions 10/21/2022

    A robust synthetic polymer platform based on naturally occurring amino acids, TheraPEA was designed to address limitations associated with the use of traditional polymeric materials.

  6. Available Fill/Finish Capacity With Exceptional Manufacturing Flexibility 2/15/2023

    We can fill a wide range of container sizes and volumes in the clinical and commercial manufacturing of sterile injectables. Explore our capabilities in formulation and scale up, manufacturing, lyophilization, and extractables and leachables.

  7. Aseptic Filling Systems For Biopharmaceutical Manufacturing 3/28/2023

    AST aseptic filling products address the unique processing requirements of biologics manufacturing to gently care for biologic products during the fill-finish process. Their highly accurate peristaltic dosing system uses single-use pharmaceutical grade tubing that has been optimized to keep shear stress to an absolute minimum. When exiting the fluid path through the filling needle, the motion control system maintains the fill needle within the container and slowly rises as the product is being dispensed to minimize splashing and foaming that could introduce stress to the product. Temperature controlled filling is also possible with the ASEPTiCell® and GENiSYS® systems. AST has experience dosing products at temperatures as low as 3°C.

  8. Controlled Expansion Of Supercritical Solutions (CESS®) Technology 4/24/2023

    Nanoform’s award-winning Controlled Expansion of Supercritical Solutions (CESS®) technology is a bottom-up nanoparticle engineering approach that enables the creation of API nanoparticles and can unlock the full therapeutic potential of small molecule drugs.

  9. Bionanoparticle Technology 4/24/2023

    Nanoform’s proprietary bionanoparticle technology can deliver large-molecule drug particles as small as 50 nm while retaining biological activity. This can not only enable more patient-friendly approaches to drug delivery, but also potentially higher loads of active ingredients.

  10. Pharmaceutical Vial Filling Machine With Isolator 5/3/2023

    Rotary filler for clinical and early-stage pharma production specialized for fill finish advanced aseptic manufacturing for pharmaceutical and biologics injectables. Designed to be used in an isolator.