Oral Drug Delivery Resources
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Formulation Development Strategy For Early Phase Human Studies
1/27/2022
Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.
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Solid Form Strategies For Increasing Oral Bioavailability
Optimizing a drug’s solid form can improve its solubility and bioavailability when further molecular modifications are prohibitive.
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Managing Poor Solubility With Cutting-Edge Formulation Approaches
8/24/2022
An increasing number of poorly soluble APIs are the cornerstone of cutting-edge therapies, necessitating equally complex formulation technologies to maintain or improve solubility and, ultimately, bioavailability.
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Evolution Of Novel Polymers To Overcome Limits In Sustained Drug Delivery
10/24/2022
Degradable polymers evolved from aliphatic polyesters to nitrogen-bearing biomaterials such as polyurethanes and polyester amides. Explore a brief history of the development of PEA polymers.
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Patient Adherence With A Novel Dosage Form
11/13/2025
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Advancements In GLP-1 Analog Formulation: Overcoming Challenges
2/3/2025
Oral GLP-1 formulations represent a groundbreaking advance in obesity treatment to offer improved patient comfort and adherence while expanding the therapeutic market.
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Spray Drying For Improved Solubility
11/15/2022
Gain expert insights into how to develop a spray dried powder formulation and scale it from early feasibility studies to commercial manufacturing.
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Formulation Development For Injectables
6/13/2023
A uniquely modified cyclodextrin is emerging as a versatile and indispensable tool for development. Explore how the right formulation approach can enhance drug delivery and improve patient outcomes.
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Advances In Spray Drying For Enhanced Bioavailability And Improved Formulation Control
In a recent webinar, Lonza discussed the process it uses to develop a spray dried powder formulation and scale from early feasibility studies to manufacturing.
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Inspiring A New Era Of Patient-Centric Medicines
3/23/2023
Patients are more empowered, making it essential to promote better adherence, improve medical benefits, and bolster market perception. See the technologies enabling this shift toward patient-centricity.