Oral Drug Delivery Resources

  1. New Technologies To Improve Solubility Of Brick Dust Compounds 7/13/2022

    David Lyon, Ph.D., and Molly Adam answer attendee questions from a recent webinar about three enabling technologies designed to improve drug solubility in organic solvents for spray drying.

  2. Opioid Reformulation Filed As A CMC Supplement In Less Than A Year 4/1/2019

    Some reformulation projects are more challenging than others. See how innovative processing equipment from Freund-Vector was leveraged to develop an efficient and effective solution.

  3. Application Of A Novel Temperature Shift Process For Particle Engineering

    Spray drying of amorphous dispersions improves solubility and bioavailability, enabling supersaturation in the intestine and driving higher absorption rates when compared to crystalline drug forms.

  4. Solid Form Strategies For Increasing Oral Bioavailability

    Optimizing a drug’s solid form can improve its solubility and bioavailability when further molecular modifications are prohibitive.

  5. Formulation Development Strategy For Early Phase Human Studies 1/27/2022

    Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.

  6. Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives 7/17/2024

    A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.

  7. Zydis® Orally Disintegrating Tablet (ODT) Vs. Standard Tablets (ST) 7/28/2023

    Review how Zydis ODT compares against standard oral tablets, how the same molecule can produce a different outcome when utilizing Zydis ODT, and findings from over 20 published studies.

  8. Integrating Early-Phase Clinical Supply Manufacturing & Distribution 5/10/2022

    A tablet formulation was a solution when developing a new class of anti-infective medicine, allowing the integration of formulation development, clinical trial material (CTM) manufacturing, and supply and distribution to patients.

  9. Key Offerings To Help Support Your OSD On Its Journey To Market

    Examine several important factors needed to effectively support oral solid dosage therapeutic manufacturing and overcome the complexities involved.

  10. Nanoformed API: A Superior Alternative To Solid Dispersions 7/29/2024

    Cutting-edge nanotechnology is now emerging, able to address bioavailability challenges and deliver higher drug loads in more patient-friendly formats with fewer and smaller pills and easier regimens.