Oral Drug Delivery Resources

  1. Innovative ASD Technology Improves Abandoned Cancer Medication 3/1/2024

    Review this case to learn how one solid dispersion technology lowered patients' pill burdens and demonstrated an improved therapeutic response for Galeterone.

  2. Engineering Approaches To Respiratory Drug Delivery 5/27/2022

    Explore the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.

  3. An Insoluble Problem? Oral Drug Solubility With Functional Polymers 6/2/2022

    Review the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility and common questions on the topic.

  4. Crystallization Process Dev: Ramping Up Bench-Scale Control 1/20/2022

    Since physical structure and biological activity are directly linked, controlling the physical form of a compound is paramount to a final drug product’s quality and effectiveness.

  5. Reducing Environmental Impact At All Stages Of The Medicine Journey

    Explore how utilizing technologies like AI and digital twinning can inform decision-making at the R&D stage and how to optimize the delivery of the final drug product to patients with greener logistics.

  6. Improved Bioavailability In 12 Weeks 2/26/2018

    A lead compound showed clinical promise but had limited bioavailability owing to low solubility. Learn about the challenges, including the molecular characterization and limited budget, and the structured 3-step approach.

  7. Steps To Overcome Challenges Associated With Biologic Formulation Development 8/24/2022

    Explore guidance on the challenges posed by biologics, including overcoming degradation, establishing a stress test process, and the value of lipid nanoparticles (LNPs) and polymeric nanoparticles (NPs).

  8. Solid Form Strategies For Increasing Oral Bioavailability

    Optimizing a drug’s solid form can improve its solubility and bioavailability when further molecular modifications are prohibitive.

  9. Enabling Long Lasting Clinical Outcomes In Coronary Stenting 9/12/2022

    Polyester amides (PEAs) bring several desired and differentiating properties to drug-eluting stent (DES) applications for treating coronary artery disease (CAD).

  10. Layer By Layer: 3D Screen Printing And The Future Of Drug Development 8/15/2025

    3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.