Oral Drug Delivery Resources

  1. Strategies For De-Risking Early-Phase Oral Small Molecule Drug Development 3/7/2022

    A team of experts discuss risk-reduction strategies, critical formulation considerations, and careful technology selection to stretch the often limited quantities of API available for early studies.

  2. Amorphous Formulations For Insoluble Drugs: Rational Design & Practical Approaches On Formulation Screening & Development 1/26/2022

    The issues associated with amorphous formulations include solid state stability, chemical stability, reproducibility of API manufacturing, impurity of API, in vitro in vivo performance, process and scale-up.

  3. Optimizing Formulations With Bioavailability Enhancement Technologies

    API-sparing development techniques and identifying the appropriate scalable formulation technology to improve drug solubility and enhance oral bioavailability can help increase your chances of success.

  4. Overcoming Supply Chain Roadblocks To Ensure Reliable Complex OSD Delivery 2/26/2024

    Ensuring critical oral solid dosage (OSD) therapeutics reach patients successfully relies on the ability of developers and manufacturers to navigate the inherent issues surrounding their increasing complexity.

  5. Recent Innovations And Enhancements To Pharmaceutical Spray Drying

    Finding alternative solvent approaches could allow for lower volumes of less toxic solvents, significantly improving both the environmental and human health implications of new drugs produced.

  6. Leveraging Tools To Create Optimized Solutions 7/17/2024

    Review the key trends and challenges shaping the CDMO industry as well as the tools helping a leading CDMO meet the growing demand for pediatric formulations and taste-masking solutions.

  7. Steps To Overcome Challenges Associated With Biologic Formulation Development 8/24/2022

    Explore guidance on the challenges posed by biologics, including overcoming degradation, establishing a stress test process, and the value of lipid nanoparticles (LNPs) and polymeric nanoparticles (NPs).

  8. Solubility With Lipid-Based Technologies For Oral & Injectable Formulations 11/7/2022

    Innovative approaches in developing formulations can help to improve a drug's safety and efficacy. Explore the decision for selecting the best-suited technology for formulating a complex molecule.

  9. Formulation Research Strategy For Discovery- Stage New Drug Candidates 1/24/2022

    Early stage formulation studies, which should support the emerging target product profile, will often yield important experimental results to aid subsequent development of clinically relevant dosage forms.

  10. Accelerating The Development Of Oncology Medicines 3/3/2022

    Oncology drug development has seen a significant shift in focus, as molecule chemistries and drug technologies have improved. Explore five areas for consideration and the potential emerging solutions.