Oral Drug Delivery Resources

81. Opioid Reformulation Filed As A CMC Supplement In Less Than A Year 4/1/2019

    Some reformulation projects are more challenging than others. See how innovative processing equipment from Freund-Vector was leveraged to develop an efficient and effective solution.

82. Less Mess, Less Stress, Best Expressed: An Alternative To Spray Drying 7/16/2024

    Although well-established processes, spray drying and hot-melt extrusion can be outperformed in bioavailability, cost-savings, manufacturing speed, environmental impact, and more.

83. Semi-Solid And Semi-Liquid Dosage Forms: What To Know 3/7/2023

    Interest in semi-solid dose (SSD) forms has been on the rise. Learn more about the advantages of formulating medications into SSD forms as well as the challenges to consider.

84. Using Advanced Technologies To Formulate Complex Molecules

    In this survey, 200+ people involved in the oral dose market shared their views on barriers to the development of oral formulations and technological responses to them.

85. Amorphous Formulations For Insoluble Drugs: Rational Design & Practical Approaches On Formulation Screening & Development 1/26/2022

    The issues associated with amorphous formulations include solid state stability, chemical stability, reproducibility of API manufacturing, impurity of API, in vitro in vivo performance, process and scale-up.

86. Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets 1/27/2025

    Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.

87. Enhancing The Solubility Of High Lipophilicity Drugs Via Spray Drying 3/10/2023

    A new R&D project shows the solubility and dissolution characteristics of Itraconazole can be improved by helping them maintain an amorphous state after spray drying with selected hydrophilic polymers.

88. A Smarter Strategy For Optimizing Oncology Drug Products 7/14/2023

    John McDermott, VP of Scientific Consulting, shares insights on the benefits of evaluating targeted oncology molecules in healthy volunteers and applying an effective platform to accelerate drug product optimization.

89. Early Solid Form Screening To Guide Drug Development

    Conducting solid form screening early can help your team select and isolate the ideal lead polymorph to ensure manufacturability and stability while avoiding costs and hiccups down the road.

90. Rational Design Of Oral Nanosuspensions For Insoluble Drugs 1/26/2022

    The advantages of nanosuspension dosage forms include improving bioavailability and API stability, increasing drug loading, better dose flexibility and accuracy, and easy swallowing for pediatric or geriatric populations.