Oral Drug Delivery Resources

  1. Procuring Packaging And Delivery Systems: Single Versus Dual Sourcing 6/2/2026

    In this article, Fran DeGrazio examines the trend toward dual sourcing of products, components, and materials for drug delivery packaging and systems. She outlines the key differences between single and dual sourcing and makes recommendations about using one versus the other while mitigating supply chain and product quality risk. 

  2. Nanoformed API: A Superior Alternative To Solid Dispersions 7/29/2024

    Cutting-edge nanotechnology is now emerging, able to address bioavailability challenges and deliver higher drug loads in more patient-friendly formats with fewer and smaller pills and easier regimens.

  3. 5 Novel Techniques For Solubility Enhancement 2/28/2022

    Thanks to insoluble drug delivery technologies, the practice of reformulating poorly soluble drug products to improve efficacy, patient compliance and safety has now been widely adopted.

  4. The Role Of Micronization In The Journey To Drug Product Development

    Micronization is an incredibly important step of the process of transitioning a compound from initial discovery into the clinic. Learn more about the key benefits of micronization.

  5. Improve Solubility And Spray Drying Throughput For Brick Dust Compounds

    This paper presents three approaches to address poor solubility in organic solvents for spray drying as well as case studies outlining their successful application during development.

  6. A Custom Pill For Every Patient 6/4/2024

    By enabling the creation of personalized medications and offering a wider range of products, 3D printing technology has the potential to enhance patient care and improve the healthcare experience.

  7. Early Solid Form Screening To Guide Drug Development

    Conducting solid form screening early can help your team select and isolate the ideal lead polymorph to ensure manufacturability and stability while avoiding costs and hiccups down the road.

  8. From Nanoformed Powder To 3D Printable Ink 3/22/2023

    3D printing in pharmaceutics is advancing to offer innovative drug delivery applications. Explore the possibilities of forming stable suspension in printing ink from nanoformed materials.

  9. A Phase I Study Allowing Clinical Screening Of Multiple Solubility-Enhancement Formulation Technologies 3/7/2022

    The study was designed to assess the clinical performance of prototype formulations, assess food effect and dose linearity of a selected formulation, and the impact on exposure in subjects taking proton pump inhibitors (PPI).

  10. Amorphous Formulations For Insoluble Drugs: Rational Design & Practical Approaches On Formulation Screening & Development 1/26/2022

    The issues associated with amorphous formulations include solid state stability, chemical stability, reproducibility of API manufacturing, impurity of API, in vitro in vivo performance, process and scale-up.