Featured Editorial

  1. Drug Delivery Trends From 2025: Top 4 For Momentum Gains In 2026 12/2/2025

    In this article, Fran DeGrazio identifies four notable trends in drug delivery that gained momentum in 2025 and, she predicts, will continue to do so in 2026 and beyond. They are digitalization, sustainability, patient centricity, and the advanced delivery of complex biopharmaceuticals.

  2. The Blue Crayfish: Turning Nature's Efficiency Into Safe, Bioavailable Therapeutics 12/1/2025

    Crayfish achieve incredibly rapid biomineralization — a physiological marvel that is now setting the stage for a new class of highly bioavailable mineral-based therapeutic agents.

  3. Formulation And Delivery Considerations For Cell And Gene Therapies 11/25/2025

    How can we ensure cell and gene therapies are truly transformative for patients? Success depends on the right combination of formulation, preparation, and delivery.

  4. Emerging RNA Delivery Strategies For Solid Tumor Oncology 11/20/2025

    RNA shows promise in solid tumors, but delivery remains the core challenge. New targeting and delivery strategies aim to overcome tumor barriers and unlock RNA’s full therapeutic potential.

  5. What Do Patients Appreciate? Therapeutic Innovation And Accessibility 11/11/2025

    At the PODD 2025 conference, patient advocates telling their own treatment stories focused on innovations in therapies and delivery methods for targeting chronic and rare diseases, leveraging technologies such as gene editing and subcutaneous delivery of complex biologics. In this article, Chief Editor Tom von Gunden carries forward the patient-centric themes of convenience and accessibility.

  6. How Can We Develop New Treatments For Patients With Early Breast Cancer? 11/10/2025

    Intensity Therapeutics has developed a new approach to treating cancer — a therapy injected directly into tumors that kills cancer and stimulates a potent anticancer immune response.

  7. M&A In GLP-1 Technology: Practical Recommendations And Best Practices 11/4/2025

    With explosive demand, expanding indications, and rapid innovation, the GLP-1 revolution is reshaping dealmaking. Here's a practical guide for companies negotiating M&A in this arena.

  8. Drug Delivery Innovation: Getting Advanced Therapies To Patients 11/3/2025

    In this article, Fran DeGrazio recounts the evolution of drug delivery technologies as she underscores the need to innovate in the delivery of advanced therapies. Considering chronic diseases, rare diseases, and difficult-to-reach therapeutic targets, Fran offers suggestions for organizing and readying for the development and delivery of platforms, systems, and devices for next generation treatments, including personalized, precision medicines.

  9. Video Spotlight: Where Science Meets Magic with MIT Institute Professor Robert S. Langer 10/29/2025

    Drug Discovery Online interviews MIT’s Bob Langer on biomedical innovation, personalized medicine, longevity, and entrepreneurship—highlighting his journey, lab impact, and personal discipline.

  10. Developing Exosome-Based RNA Therapeutics For CNS Regeneration 10/24/2025

    Inside the effort to use exosomes as natural nanocarriers that deliver RNA therapeutics safely across the blood–brain barrier to heal damaged neural tissue.