Infusion Drug Delivery Articles

1. How Targeted Nanoparticles And Circular RNA Are Advancing CAR-T Development 7/2/2026

   To overcome the short duration of therapeutic protein expression associated with mRNA, Sail Biomedicine has developed novel endless RNA constructs. Michael Lam, Ph.D., discusses its delivery mechanisms and an outlook for future applications.

2. Why Improving Drug Delivery Remains A Major Opportunity In Oncology 6/12/2026

   Engineered oncolytic viruses are emerging as a promising way to target tumors, deliver immune-stimulating payloads, and improve treatment of metastatic cancer.

3. Crossing The Brain's Barrier: Recent Advances And What Lies Ahead 6/11/2026

   Recent FDA approvals mark a breakthrough in blood-brain barrier drug delivery, validating brain-shuttle technologies and accelerating new CNS therapies.

4. The Hidden Operational Complexities Of Home Infusion 5/20/2026

   Home infusion can lower costs and improve access, but requires complex coordination, patient readiness, logistics, and monitoring to ensure safe and effective care.

5. Need A Drug Delivery Conversation Starter? Try Target Product Profile 5/18/2026

   In this article, Chief Editor Tom von Gunden explores the need for and existence of cross-functional communication during drug product development and delivery device selection. He consults industry veterans with experience in various formulation or delivery roles at GSK and Merck. They identify the Target Product Profile (TPP) as the core concept guiding collaboration. 

6. Transendocardial Cell Delivery In Post‑Acute Myocardial Infarction 5/4/2026

   Optimized delivery technologies will be central to next-generation therapies, serving as key differentiators for both clinical efficacy and operational feasibility.

7. BCS Class IV: Rescuing Hard To Deliver Molecules With Nanoformulation 4/23/2026

   BCS Class IV drugs have low solubility and permeability. Oral nanoparticles can overcome both barriers, offering a more effective and tunable oral delivery strategy.

8. Patient-Centric Drug Delivery: Do Possible And Preferable Always Align? 4/22/2026

   In this article, Chief Editor Tom von Gunden discusses the alignment of drug delivery method with patient preference and need. He reflects on recent conversations in which he heard from experts in drug and delivery product development, as well as patients themselves, about patient-centric considerations such as safety, efficacy, usability, and convenience. The primary use case is the transition from clinically administered IV to subcutaneous injection, including self-administration.

9. AI, Digitalization, And In Vivo Programming Redefine Cell And Gene Therapy 4/20/2026

   By merging precision genetic engineering with the scalability of nanomedicine and the predictive power of AI, scientists are reshaping the future of human health.

10. Nanosystems And Rare Diseases: Opportunities And Limitations 3/27/2026

    Nanosystems offer unique capabilities, enabling researchers to design precise, versatile delivery systems that address key challenges in rare diseases.