Oral Drug Delivery Resources

  1. How Lipid Nanoparticles Overcome Solubility Challenges 3/7/2023

    More than 80% of NCEs are poorly soluble compounds. Overcoming this challenge using lipid nanoparticles is essential to move your drug product through the pipeline and into the market.

  2. A Solvent-Free, Fusion-Based ASD Manufacturing Process 3/5/2024

    Explore a solvent-free alternative for the production of amorphous solid dispersions (ASDs) that not only improves manufacturability but also reduces the carbon footprint of ASD manufacturing.

  3. Liquid Capsule Manufacturing: What To Know 5/4/2022

    Capsules surround a drug in an unflavored, solid barrier enclosure. This article focuses on liquid capsule manufacturing and its advantages.

  4. Application Of A Novel Temperature Shift Process For Particle Engineering

    Spray drying of amorphous dispersions improves solubility and bioavailability, enabling supersaturation in the intestine and driving higher absorption rates when compared to crystalline drug forms.

  5. Accelerating The Development Of Oncology Medicines 3/3/2022

    Oncology drug development has seen a significant shift in focus, as molecule chemistries and drug technologies have improved. Explore five areas for consideration and the potential emerging solutions.

  6. Crystallization Process Dev: Ramping Up Bench-Scale Control 1/20/2022

    Since physical structure and biological activity are directly linked, controlling the physical form of a compound is paramount to a final drug product’s quality and effectiveness.

  7. The Flux Performance Of Nanoformed And Untreated PRX Solid Suspensions 7/26/2023

    Explore the application of in vitro flux assays to nanoparticles, with data on how the in vitro permeability apparatus can characterize the membrane flux performance of an API formulated as a nanosuspension.

  8. Advances In Spray Drying For Enhanced Bioavailability And Improved Formulation Control

    In a recent webinar, Lonza discussed the process it uses to develop a spray dried powder formulation and scale from early feasibility studies to manufacturing.

  9. The Evolution Of A CDMO 7/17/2024

    Transitioning from a product-based to a service-based organization helped a leading CDMO commit to client-centricity and operational excellence and meet the evolving needs of the pharmaceutical industry.

  10. An Easy-To-Swallow Depression Drug For Elderly Patients 4/20/2023

    Examine how an innovative formulation approach helped a developer create a version of their drug that promotes treatment compliance within the geriatric population.