Oral Drug Delivery Resources
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Achieve Release Profiles And Select Excipients For Formulation Development
5/2/2020
The formulation and manufacture of modified-release OSD forms are highly specialized. Review considerations for planning and executing a successful modified release oral solid dosage formulation.
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Benefits Of Microparticle Technology For Oral Drug Solubility Enhancement
6/8/2022
Spray-dried dispersions, hot-melt extrusion, and solubilizing excipients are common solubility enhancement techniques, but new developments to maximize amorphous solid dispersion benefits are needed.
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Application Of Nano-Emulsion Technology To Address Unmet Medical Needs: A Case Study Of Clopidogrel IV By 505(b)(2) Pathway
1/26/2022
Review a process where the insoluble and unstable free-base form of clopidogrel is converted to a form with acceptable drug loading and is protected from chemical degradation.
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An Insoluble Problem? Oral Drug Solubility With Functional Polymers
6/2/2022
Review the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility and common questions on the topic.
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Innovating Drug Dosage Forms And Supporting Patient-Centric Goals
Learn how delivering HPAPI drugs in OSD form can help boost patient compliance and consider the formulation challenges inherent to HPAPI development and manufacturing.
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New Technologies To Improve Solubility Of Brick Dust Compounds
7/13/2022
David Lyon, Ph.D., and Molly Adam answer attendee questions from a recent webinar about three enabling technologies designed to improve drug solubility in organic solvents for spray drying.
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Rational Design & Development Of Lipid- Filled Hard Capsules
1/26/2022
With the increasing percentage of water-insoluble or low permeable new therapeutic entities among drug pipelines, lipid-based drug delivery systems have become an important tool for formulation development.
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Maintaining Drug Bioavailability And Masking Taste With Microencapsulation
8/24/2022
Several technologies are available for microencapsulating drugs. Finding the right CDMO to optimize a drug’s efficacy and manufacturing during formulation is integral to its clinical and commercial success.
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From Nanoformed Powder To 3D Printable Ink
3/22/2023
3D printing in pharmaceutics is advancing to offer innovative drug delivery applications. Explore the possibilities of forming stable suspension in printing ink from nanoformed materials.
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Advances In Spray Drying For Enhanced Bioavailability And Improved Formulation Control
In a recent webinar, Lonza discussed the process it uses to develop a spray dried powder formulation and scale from early feasibility studies to manufacturing.