Oral Drug Delivery Resources

  1. Application Of A Novel Temperature Shift Process For Particle Engineering

    Spray drying of amorphous dispersions improves solubility and bioavailability, enabling supersaturation in the intestine and driving higher absorption rates when compared to crystalline drug forms.

  2. Reformulation Of A Complex, High-Drug-Load, Modified Release Dosage Form 4/5/2021

    What if you could limit and position a formulation change as only a CMC prior approval supplement under the FDA’s scale-up and post-approval changes guidance?

  3. Strategies For Optimal Scale-Up, Tech Transfer Of Oral Small Molecules

    Learn about the identification of CMAs, CPPs, and CQAs of drug products and how to predict their impact on formulation and manufacturing processes.

  4. Improved Biomanufacturing Processes And Drug Product Stability 9/20/2022

    Improve upstream media for bioavailability and foam stability, downstream buffers for purification, and the formulation and final fill drug product stability with this highly interdisciplinary process.

  5. Strategies To Mitigate Common Pitfalls In Early Drug Development 3/4/2022

    Two experts discuss the ways companies can address issues with low bioavailability and the benefits of enlisting an experienced drug development partner.

  6. Crystallization Process Development: Peptide Crystallization 1/24/2022

    Whether performed during formation of an API or as a means to purify intermediates, achieving control of nucleation and crystal growth is critical to designing a successful peptide crystallization process.

  7. Dosage Form Optimization For Patient-Centric Drug Development Process

    Designing products with patients in mind by utilizing superior formulation and drug delivery technologies in the early phases of development can minimize risks on the path to market.

  8. Accelerate Development Of Enabled Formulations For Poorly Soluble Drugs 8/21/2023

    Explore how a platform integrating drug substance, drug product, and clinical testing within a single organization accelerates development and reduces costs, helping deliver positive outcomes earlier.

  9. Accelerating The Development Of Oncology Medicines 3/3/2022

    Oncology drug development has seen a significant shift in focus, as molecule chemistries and drug technologies have improved. Explore five areas for consideration and the potential emerging solutions.

  10. Opioid Reformulation Filed As A CMC Supplement In Less Than A Year 4/1/2019

    Some reformulation projects are more challenging than others. See how innovative processing equipment from Freund-Vector was leveraged to develop an efficient and effective solution.