Oral Drug Delivery Resources

  1. Enhancing The Solubility Of High Lipophilicity Drugs Via Spray Drying 3/10/2023

    A new R&D project shows the solubility and dissolution characteristics of Itraconazole can be improved by helping them maintain an amorphous state after spray drying with selected hydrophilic polymers.

  2. The Evolution Of A CDMO 7/17/2024

    Transitioning from a product-based to a service-based organization helped a leading CDMO commit to client-centricity and operational excellence and meet the evolving needs of the pharmaceutical industry.

  3. A Technical Package That Serves On-Time Injectable Project Completion 4/24/2023

    The accuracy, robustness, and completeness of the technical package an organization submits to its development and/or manufacturing partner is critical to meeting fill project timelines.

  4. Innovative Formulation Technologies By 505(b)(2) Regulatory Pathway 1/24/2022

    Revitalization of older marketed drugs using innovative drug delivery technologies can provide new marketing exclusivity and patent protection, offering an effective tool for product life cycle management.

  5. Seven Softgel Myths: Are You Missing Your Softgel Opportunity?

    Softgels are a popular dose format among consumers, thanks to their high swallowability and quick onset of action, yet pharmaceutical developers may not even consider them. Why the disconnect?

  6. A Smarter Strategy For Optimizing Oncology Drug Products 7/14/2023

    John McDermott, VP of Scientific Consulting, shares insights on the benefits of evaluating targeted oncology molecules in healthy volunteers and applying an effective platform to accelerate drug product optimization.

  7. Recent Innovations And Enhancements To Pharmaceutical Spray Drying

    Finding alternative solvent approaches could allow for lower volumes of less toxic solvents, significantly improving both the environmental and human health implications of new drugs produced.

  8. Benefits Of Microparticle Technology For Oral Drug Solubility Enhancement 6/8/2022

    Spray-dried dispersions, hot-melt extrusion, and solubilizing excipients are common solubility enhancement techniques, but new developments to maximize amorphous solid dispersion benefits are needed.

  9. Formulation Development From Preclinical To First-In-Human 1/24/2022

    A compound with poor biopharmaceutical properties or improper formulation design could lead to a delay in the project or even program termination.

  10. Sophisticated Formulation Approaches For Insoluble Drug Candidates 1/24/2022

    A sophisticated drug delivery approach involves collaboration, technical experience, and years of working knowledge in drug development at different stages of the process.