Oral Drug Delivery Resources

  1. Pharmaceutical Nanotechnology: What To Know 8/10/2022

    Here is what you need to know about the key advantages that pharmaceutical nanotechnology provides in improving drug efficacy and decreasing adverse reactions.

  2. Making A Case For A Fixed Dose Combination Drug Strategy

    As patient-centricity spurs innovation in drug delivery systems, examine the potential of FDCs to provide convenient dosing and how increased patient compliance is alleviating the cost of health care.

  3. Seven Softgel Myths: Are You Missing Your Softgel Opportunity?

    Softgels are a popular dose format among consumers, thanks to their high swallowability and quick onset of action, yet pharmaceutical developers may not even consider them. Why the disconnect?

  4. Amorphous Formulations For Insoluble Drugs: Rational Design & Practical Approaches On Formulation Screening & Development 1/26/2022

    The issues associated with amorphous formulations include solid state stability, chemical stability, reproducibility of API manufacturing, impurity of API, in vitro in vivo performance, process and scale-up.

  5. Strategies For Accelerating The Development Of Modified Release Oral Forms 3/3/2022

    Careful selection of appropriate excipients and delivery technologies is key to the design of modified release (MR) formulations fulfilling specific performance requirements.

  6. A Smarter Strategy For Optimizing Oncology Drug Products 7/14/2023

    John McDermott, VP of Scientific Consulting, shares insights on the benefits of evaluating targeted oncology molecules in healthy volunteers and applying an effective platform to accelerate drug product optimization.

  7. Strategies For De-Risking Early-Phase Oral Small Molecule Drug Development 3/7/2022

    A team of experts discuss risk-reduction strategies, critical formulation considerations, and careful technology selection to stretch the often limited quantities of API available for early studies.

  8. Harness High-Quality PBPK Modeling To Enhance Clinical Readiness

    Physiologically based pharmacokinetic (PBPK) modeling advancements are helping drug sponsors mitigate risk in preclinical and clinical studies through early identification of poor absorption properties.

  9. Developing A Multi-Drug Combination, Antiparasitic Drug For Dogs 4/13/2022

    Discover how it worked to manufacture clinical supplies of flavored tablets with multiple APIs in just six months while ensuring content uniformity and stability.

  10. Application Of Nano-Emulsion Technology To Address Unmet Medical Needs: A Case Study Of Clopidogrel IV By 505(b)(2) Pathway 1/26/2022

    Review a process where the insoluble and unstable free-base form of clopidogrel is converted to a form with acceptable drug loading and is protected from chemical degradation.