Oral Drug Delivery Resources

  1. Evolution Of Novel Polymers To Overcome Limits In Sustained Drug Delivery 10/24/2022

    Degradable polymers evolved from aliphatic polyesters to nitrogen-bearing biomaterials such as polyurethanes and polyester amides. Explore a brief history of the development of PEA polymers.

  2. Age-Appropriate Pediatric Formulation Development 1/27/2022

    There is a significant variability in the pharmacokinetics of the same drug and dosage form between pediatric and adult populations, and the factors impacting drug bioavailability are different in children.

  3. Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives 7/17/2024

    A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.

  4. Increasing Bioavailability With Amorphous Solid Dosage Formulations 11/10/2023

    Discover the challenges associated with pH-dependent solubility for oral tyrosine kinase inhibitor drugs and how leveraging ASD formulation can help create more effective, patient-friendly drug products.

  5. A Solvent-Free, Fusion-Based ASD Manufacturing Process 3/5/2024

    Explore a solvent-free alternative for the production of amorphous solid dispersions (ASDs) that not only improves manufacturability but also reduces the carbon footprint of ASD manufacturing.

  6. Enhancing The Solubility Of High Lipophilicity Drugs Via Spray Drying 3/10/2023

    A new R&D project shows the solubility and dissolution characteristics of Itraconazole can be improved by helping them maintain an amorphous state after spray drying with selected hydrophilic polymers.

  7. 10 Ways To Align Your Medical Device With Human Factors Industry Best Practices 3/1/2024

    Discover how patient-centric design principles can improve the development of medical devices. By focusing on user needs and behaviors, manufacturers can ensure that products align with expectations.

  8. Wet Milling Vs. Dry Milling In The Pharmaceutical Industry 8/10/2022

    Read about the considerations necessary for choosing between wet milling and dry milling for a specific active pharmaceutical ingredient.

  9. Solid Form Screening, Rapid Formulation Selection To Meet Tight Timelines

    A comprehensive approach to evaluating drug molecules for the selection of a lead solid form and formulation can significantly accelerate development timelines and limit risks in later development.

  10. Patient Adherence With A Novel Dosage Form 11/13/2025

    A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.