Oral Drug Delivery Resources

  1. Achieve Release Profiles And Select Excipients For Formulation Development 5/2/2020

    The formulation and manufacture of modified-release OSD forms are highly specialized. Review considerations for planning and executing a successful modified release oral solid dosage formulation.

  2. Developing And Manufacturing Drugs With HPAPIs 1/27/2025

    Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.

  3. Streamline Early-Stage Development To Reach The Clinic Faster 7/17/2023

    Early-stage development is an iterative process, continuously generating new data and insights to optimize the product based on emerging knowledge.

  4. Liquid Capsule Manufacturing: What To Know 5/4/2022

    Capsules surround a drug in an unflavored, solid barrier enclosure. This article focuses on liquid capsule manufacturing and its advantages.

  5. Rational Design & Development Of Lipid- Filled Hard Capsules 1/26/2022

    With the increasing percentage of water-insoluble or low permeable new therapeutic entities among drug pipelines, lipid-based drug delivery systems have become an important tool for formulation development.

  6. Application Of A Novel Temperature Shift Process For Particle Engineering

    Spray drying of amorphous dispersions improves solubility and bioavailability, enabling supersaturation in the intestine and driving higher absorption rates when compared to crystalline drug forms.

  7. Overcoming Supply Chain Roadblocks To Ensure Reliable Complex OSD Delivery 2/26/2024

    Ensuring critical oral solid dosage (OSD) therapeutics reach patients successfully relies on the ability of developers and manufacturers to navigate the inherent issues surrounding their increasing complexity.

  8. Making A Case For A Fixed Dose Combination Drug Strategy

    As patient-centricity spurs innovation in drug delivery systems, examine the potential of FDCs to provide convenient dosing and how increased patient compliance is alleviating the cost of health care.

  9. Application Of Nano-Emulsion Technology To Address Unmet Medical Needs: A Case Study Of Clopidogrel IV By 505(b)(2) Pathway 1/26/2022

    Review a process where the insoluble and unstable free-base form of clopidogrel is converted to a form with acceptable drug loading and is protected from chemical degradation.

  10. Managing Poor Solubility With Cutting-Edge Formulation Approaches 8/24/2022

    An increasing number of poorly soluble APIs are the cornerstone of cutting-edge therapies, necessitating equally complex formulation technologies to maintain or improve solubility and, ultimately, bioavailability.