Oral Drug Delivery Resources

31. A Clinical Assessment Of Delayed-Release Coated Capsule Compositions For Regional Gastrointestinal Delivery Using Gamma Scintigraphy 3/7/2022

    Gamma scintigraphy was used to evaluate GI transit and release from 3 capsule prototypes with different coating systems; data on pH, temperature and pressure during GI transit was obtained and correlated.

32. Formulation Development Strategy For Early Phase Human Studies 1/27/2022

    Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.

33. Integrated First-In-Human Services To Streamline End-To-End Development And Manufacturing 6/1/2022

    Lonza’s SimpliFiH^®️ Solutions offering is designed to simplify and accelerate the development pathway, even for APIs with challenging properties, such as low aqueous solubility and poor bioavailability.

34. How Oral GLP-1 Therapies Are Revolutionizing Obesity Treatment 2/3/2025

    The rising incidence and severity of obesity have amplified a therapeutic need in healthcare. Read more about Dr. Srinivasan Shanmugam discussing the challenges and impact of GLP-1 analogs.

35. Rational Design Of Oral Nanosuspensions For Insoluble Drugs 1/26/2022

    The advantages of nanosuspension dosage forms include improving bioavailability and API stability, increasing drug loading, better dose flexibility and accuracy, and easy swallowing for pediatric or geriatric populations.

36. 4 Factors Affecting Solubility Of Drugs 2/28/2022

    Improper drug solubility can lead to suboptimal drug delivery and absorption, resulting in ineffective drug efficacy and side effects, so solubility must be evaluated in the early stages of drug discovery.

37. Reshaping Drug Development With 3D Screen Printing 8/15/2025

    Steven Facer and Laxxon Medical COO Klaus Kühne describe the capabilities of 3D screen printing for pharmaceutical production. Explore prototyping, IP protection, release profile possibilities, and more.

38. Choosing A Formulation And Process Approach To OCR Products 11/5/2018

    Do you want to develop an oral controlled release (OCR) product? Understand the options and their ramifications as the first step toward devising a plan.

39. Platform Reduces Product Development Time And Cost By 30% 3/4/2022

    Using innovative capsule-filling equipment and processing technology, and mini-tablet and drug-layered beadlet manufacturing, you can have an adaptable, easily modified formulation.

40. Improved Biomanufacturing Processes And Drug Product Stability 9/20/2022

    Improve upstream media for bioavailability and foam stability, downstream buffers for purification, and the formulation and final fill drug product stability with this highly interdisciplinary process.