Oral Drug Delivery Resources

  1. Solving Delivery Challenges For Tolerogenic Vaccines

    Explore the advantages offered by an orally dissolving tablet platform relating to large molecule storage, aggregation, and, in some cases, protease activity.

  2. How To Leverage Modeling And Simulation In The Candidate Development Stage 10/27/2022

    Modeling and simulation provides another way to predict the clinical performance of a molecule, based on a robust and holistic approach, before investing the required time and money.

  3. A Phase I Study Allowing Clinical Screening Of Multiple Solubility-Enhancement Formulation Technologies 3/7/2022

    The study was designed to assess the clinical performance of prototype formulations, assess food effect and dose linearity of a selected formulation, and the impact on exposure in subjects taking proton pump inhibitors (PPI).

  4. Formulation Development Strategy For Early Phase Human Studies 1/27/2022

    Determining bioavailable formulation for animal PK, GLP toxicity, first-in-human, and first-in-patient is challenging. Drug delivery systems are usually used for poorly soluble and bioavailable compounds.

  5. Integrated Strategies for Achieving Regulatory Milestones Faster 10/12/2023

    Learn how an innovative formulation platform reduced development timelines and allowed a sponsor to find the optimal nafamostat formulation without adding unnecessary delays.

  6. Enabling Long Lasting Clinical Outcomes In Coronary Stenting 9/12/2022

    Polyester amides (PEAs) bring several desired and differentiating properties to drug-eluting stent (DES) applications for treating coronary artery disease (CAD).

  7. Unlocking A Patient Preference For Rapid Onset In Treating Migraines

    Examine the case study and learn how formulating an orally disintegrating tablet (ODT) created a convenient dosage form with a shorter Tmax for the treatment of acute migraine.

  8. Overcoming Limitations To Achieve Uniform Dosing 1/24/2022

    An immediate need for lower dose capsules in the clinic posed several challenges in blend formulation with very tight timelines for delivery.

  9. Seven Softgel Myths: Are You Missing Your Softgel Opportunity?

    Softgels are a popular dose format among consumers, thanks to their high swallowability and quick onset of action, yet pharmaceutical developers may not even consider them. Why the disconnect?

  10. Patient-Centric Solutions To Optimize Medication Adherence

    Explore how orally disintegrating tablets act as a patient-centric solution to various factors that impact treatment adherence rates across various diseases.