Oral Drug Delivery Resources

  1. Harness High-Quality PBPK Modeling To Enhance Clinical Readiness

    Physiologically based pharmacokinetic (PBPK) modeling advancements are helping drug sponsors mitigate risk in preclinical and clinical studies through early identification of poor absorption properties.

  2. Enhancing The Solubility Of High Lipophilicity Drugs Via Spray Drying 3/10/2023

    A new R&D project shows the solubility and dissolution characteristics of Itraconazole can be improved by helping them maintain an amorphous state after spray drying with selected hydrophilic polymers.

  3. Rational Design & Development Of Lipid- Filled Hard Capsules 1/26/2022

    With the increasing percentage of water-insoluble or low permeable new therapeutic entities among drug pipelines, lipid-based drug delivery systems have become an important tool for formulation development.

  4. Fundamentals Of Particle Size Analysis 1/22/2025

    Explore the importance of particle size characterization and the advanced analytical techniques employed to assess micronized particles effectively.

  5. A New Framework For Identifying Nitrosamine Risks And Derisking Products 6/18/2024

    Examine a new methodology that holds significant promise for identifying APIs at risk for NDSRI formation, enabling manufacturers to prioritize risk mitigation strategies and ensure compliance.

  6. Improved Biomanufacturing Processes And Drug Product Stability 9/20/2022

    Improve upstream media for bioavailability and foam stability, downstream buffers for purification, and the formulation and final fill drug product stability with this highly interdisciplinary process.

  7. 10 Ways To Align Your Medical Device With Human Factors Industry Best Practices 3/1/2024

    Discover how patient-centric design principles can improve the development of medical devices. By focusing on user needs and behaviors, manufacturers can ensure that products align with expectations.

  8. Diagnose Absorption Risks To Improve Preclinical And Clinical Outcomes 8/8/2023

    Physiologically based pharmacokinetic modeling is a powerful tool for clinical trial design that can be leveraged alongside early development experiments to reduce costs and accelerate timelines.

  9. Achieving New Heights By Expanding Services, Talent, And Facilities 4/20/2023

    As you aim to reduce costs and ensure on-time delivery, discover the opportunities for drug formulation and commercial supply that can advance your therapy to the clinic and beyond.

  10. Optimizing Formulations With Bioavailability Enhancement Technologies

    API-sparing development techniques and identifying the appropriate scalable formulation technology to improve drug solubility and enhance oral bioavailability can help increase your chances of success.